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Supercritical Fluid Synthesis of Highly Porous Polylactide Matrices: Fundamental Features and Technology of Formation, Development and Stabilization of Polymer Foams

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Abstract

The paper studies the formation, development and stabilization of the structure of foamed amorphous D,L-polylactide after a slow (quasi-isothermal) and a fast (quasi-adiabatic) relief of the pressure of supercritical carbon dioxide used as a plasticizing/foaming agent. The following regularities have been established: (1) the values of the foam expansion factor in the process of quasi-adiabatic depressurization are significantly lower than in the quasi-isothermal regime because of significant dissipation of the “polymer–foaming agent” system internal energy due to the internal friction in the system; (2) an expansion-collapse effect is observed during the quasi-isothermal foaming; (3) at the intermediate stage between nucleation and intensive foam development, the pore nuclei growth in the plasticized polymer is self-similar. The results obtained are important for selecting foaming regimes that provide the synthesized highly porous matrices with the structural characteristics required for their use in regenerative medicine and tissue engineering.

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ACKNOWLEDGMENTS

This work was supported by the Ministry of Science and Higher Education (state assignment of the Federal Research Center “Crystallography and Photonics” RAS) as regards experimental data obtaining and the Russian Foundation for Basic Research (Project no. 18-29-06024) as regards the theoretical modeling and interpretation of the experimental data.

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Authors and Affiliations

  1. Yuri Gagarin State Technical University of Saratov, Saratov, Russia

    D. A. Zimnyakov, M. V. Alonov, E. V. Ushakova & O. V. Ushakova

  2. Institute of Precision Mechanics and Control Problems, Russian Academy of Sciences, Saratov, Russia

    D. A. Zimnyakov

  3. Institute of Photonic Technologies of the Federal Research Center “Crystallography and Photonics”, Russian Academy of Sciences, Moscow, Russia

    V. K. Popov, N. V. Minaev, S. A. Minaeva & E. O. Epifanov

Authors
  1. D. A. Zimnyakov
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  2. M. V. Alonov
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  3. E. V. Ushakova
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  4. O. V. Ushakova
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  5. V. K. Popov
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  6. N. V. Minaev
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  7. S. A. Minaeva
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  8. E. O. Epifanov
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Correspondence to D. A. Zimnyakov.

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Zimnyakov, D.A., Alonov, M.V., Ushakova, E.V. et al. Supercritical Fluid Synthesis of Highly Porous Polylactide Matrices: Fundamental Features and Technology of Formation, Development and Stabilization of Polymer Foams. Russ. J. Phys. Chem. B 15, 1324–1328 (2021). https://doi.org/10.1134/S1990793121080182

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  • DOI: https://doi.org/10.1134/S1990793121080182

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