Abstract—Aerogel materials based on the interpolymer complex of alginate with chitosan using supercritical fluids technology were obtained. It was established that obtained aerogels have a developed mesoporous structure and a specific surface area of up to 243 m2/g. The average pore size equals 14.8 nm. The possibility of using the aerogels with the inclusion of antibiotic levomycetin as a basis for creating wound dressings was shown. It was estimated that slow release of the drug (70% during 5 h) from the aerogel matrix provides prolonged and safe supply of the drug to the surface of a wound.
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ACKNOWLEDGMENTS
This work was performed it terms of the RF Government task for the N. Laverov Federal Center for Integrated Arctic Research, RAS: “Physicochemical, genetic and morphological bases of adaptation of vegetable objects under the conditions of the changing climate of high latitudes” (no. AAAA-A18-118012390231-9, 2018–2020) using the equipment of the Center for Collective Use Arktika (Northern Arctic Federal University Named after M.V. Lomonosov) and the Center for Collective Use CT RF–Arktika (N. Laverov Federal Center for Integrated Arctic Research, RAS).
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Valchuk, N.A., Brovko, O.S., Palamarchuk, I.A. et al. Preparation of Aerogel Materials Based on Alginate–Chitosan Interpolymer Complex Using Supercritical Fluids. Russ. J. Phys. Chem. B 13, 1121–1124 (2019). https://doi.org/10.1134/S1990793119070224
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DOI: https://doi.org/10.1134/S1990793119070224