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Biocompatibility and Degradation of Porous Matrixes from Lactide and ε-Caprolactone Copolymers Formed in a Supercritical Carbon Dioxide Medium

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Abstract

Cytotoxicity and in vitro degradation rate of porous matrices based on lactide and ε-caprolactone copolymers formed via supercritical foaming are determined. A high biocompatibility of materials obtained by the above method is demonstrated.

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Authors and Affiliations

  1. Institute of Photonic Technology Federal Center Crystallography and Photonics, Russian Academy of Sciences, Troitsk, Moscow, 108840, Russia

    P. S. Timashev, N. N. Vorobieva, A. A. Akovantseva, N. V. Minaev, O. L. Zakharkina & V. N. Bagratashvili

  2. Research Institute for Physicochemical Problems, Belarusian State University, Minsk, 220080, Belarus

    Yu. A. Piskun, S. V. Kostjuk & I. V. Vasilenko

  3. Institute for Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290, Russia

    I. I. Selezneva

  4. Department of Chemistry, Moscow State University, Moscow, 119991, Russia

    N. Yu. Ignatieva, V. V. Lunin & V. N. Bagratashvili

  5. Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, 123098, Russia

    R. K. Chailakhyan

Authors
  1. P. S. Timashev
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  2. N. N. Vorobieva
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  3. A. A. Akovantseva
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  4. N. V. Minaev
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  5. Yu. A. Piskun
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  6. S. V. Kostjuk
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  7. I. I. Selezneva
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  8. I. V. Vasilenko
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  9. O. L. Zakharkina
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  10. N. Yu. Ignatieva
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  11. R. K. Chailakhyan
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  12. V. V. Lunin
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  13. V. N. Bagratashvili
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Corresponding author

Correspondence to N. N. Vorobieva.

Additional information

Original Russian Text © P.S. Timashev, N.N. Vorobieva, A.A. Akovantseva, N.V. Minaev, Yu.A. Piskun, S.V. Kostjuk, I.I. Selezneva, I.V. Vasilenko, O.L. Zakharkina, N.Yu. Ignatieva, R.K. Chailakhyan, V.V. Lunin, V.N. Bagratashvili, 2016, published in Sverkhkriticheskie Flyuidy. Teoriya i Praktika, 2016, Vol. 11, No. 2, pp. 63–74.

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Timashev, P.S., Vorobieva, N.N., Akovantseva, A.A. et al. Biocompatibility and Degradation of Porous Matrixes from Lactide and ε-Caprolactone Copolymers Formed in a Supercritical Carbon Dioxide Medium. Russ. J. Phys. Chem. B 11, 1095–1102 (2017). https://doi.org/10.1134/S199079311707017X

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  • DOI: https://doi.org/10.1134/S199079311707017X

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