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Russian Journal of Physical Chemistry B

, Volume 10, Issue 8, pp 1264–1268 | Cite as

Sterilization of a porous ultrahigh-molecular-weight polyethylene in supercritical Freons

  • D. Yu. Zalepugin
  • A. V. Maksimkin
  • M. V. Kiselevsky
  • N. A. Tilkunova
  • N. Yu. Anisimova
  • I. V. Chernysheva
  • F. S. Senatov
  • M. I. Vlasov
Article
  • 23 Downloads

Abstract

The possibility of sterilization of porous ultrahigh-molecular-weight polyethylene in subcritical Freons R22 and R410a in the absence of modifiers is for the first time demonstrated. The maximum sterilization effect is achieved when sterilization with Freon R410a is performed in static conditions for 30 min at 50°С and 250 bar or with Freon R22 for 60 min at 70°С and cyclically varied pressure within 100–290 bar (press–depress mode).

Keywords

subcritical freons sterilization press–depress mode ultrahigh-molecular-weight polyethylene 

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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • D. Yu. Zalepugin
    • 1
  • A. V. Maksimkin
    • 2
  • M. V. Kiselevsky
    • 2
    • 3
  • N. A. Tilkunova
    • 1
  • N. Yu. Anisimova
    • 2
    • 3
  • I. V. Chernysheva
    • 1
  • F. S. Senatov
    • 2
  • M. I. Vlasov
    • 1
  1. 1.Federal State Unitary Enterprise “State Plant of Medicinal Drugs”MoscowRussia
  2. 2.National University of Science and Technology “MISIS”MoscowRussia
  3. 3.Blokhin Russian Cancer Research CenterMinistry of Health of the Russian FederationMoscowRussia

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