An investigation of the dissolution of acetylsalicylic acid in supercritical carbon dioxide
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The dissolution of acetylsalicylic acid in supercritical carbon dioxide (SC–CO2) is investigated using Fourier transform IR spectroscopy. Temporal dependences of integrated intensities of the absorption band of acetylsalicylic acid (ASA) near 1199 cm–1 are measured for various ASA charges placed into a cuvette. Molar fractions of ASA in the saturated solution in SC–CO2 are determined at a temperature of 40°C and pressures of 10.0 and 15.0 MPa, and the components are 2.10 ± 0.25 × 10–4 and 11.0 ± 1.5 × 10–4, respectively.
Keywordsacetylsalicylic acid supercritical carbon dioxide IR Fourier spectroscopy solubility
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