Russian Journal of Physical Chemistry B

, Volume 10, Issue 7, pp 1085–1091 | Cite as

Hydrolysis of aralosides from Manchurian aralia to oleanolic acid and its derivatives in subcritical water

  • O. V. Filonova
  • A. V. Lekar
  • S. N. Borisenko
  • E. V. Vetrova
  • E. V. Maksimenko
  • N. I. Borisenko
  • V. I. Minkin


A method for preparing oleanolic acid (OA) and its derivatives by the hydrolysis of aralosides from Manchurian aralia in subcritical water has been developed. It has been used for the treatment of the Saparal pharmaceutical preparation at 120–240°C in a static regime. The maximal yield of OA has been obtained at 210°C.


subcritical water aralosides Manchurian aralia saponins saparal oleanolic acid HPLC–MS 


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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • O. V. Filonova
    • 1
  • A. V. Lekar
    • 1
  • S. N. Borisenko
    • 1
  • E. V. Vetrova
    • 1
  • E. V. Maksimenko
    • 1
  • N. I. Borisenko
    • 1
  • V. I. Minkin
    • 1
  1. 1.Institute of Physical and Organic ChemistrySouthern Federal UniversityRostov-on-DonRussia

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