Skip to main content
SpringerLink
Log in

Polarimetric study of rate constant for mutarotation of chiral levofloxacin, ofloxacin, sparfloxacin and ciprofloxacin drugs

  • Kinetics and Mechanism of Chemical Reactions. Catalysis
  • Published:
Russian Journal of Physical Chemistry B Aims and scope Submit manuscript

Abstract

The polarimetric study of levofloxacin, ofloxacin, Sparfloxacin and Ciprofloxacin drugs has been carried out. Specific rotation and rate constant of mutarotation has been calculated with respect to time. It was found that the specific rotation and rate constant increases with increase in time. The specific rotation of ofloxacin and ciprofloxacin was found to be greater than that of sparfloxacin and levofloxacin. On the other hand the rate constant of mutarotation for sparfloxacin and ciprofloxacin was found to be greater than that of levofloxacin and ofloxacin.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. M. Dubrunfaut, C. R. Acad. Sci. 23, 38 (1846).

    Google Scholar 

  2. B. Anderson and P. E. Broe, Acta Chem. Scand. 26, 3691 (1972).

    Article  Google Scholar 

  3. A. P. Dubrunfaut, Ann. Chim. Phys. 3, 18 (1846).

    Google Scholar 

  4. J. N. Bronsted and E. A. Guggenheim, J. Am. Soc. 49, 2554 (1927).

    Article  CAS  Google Scholar 

  5. C. G. Swain, J. Am. Chem. Soc. 72, 4578 (1950).

  6. M. Cockmann, D. G. Kubler, A. S. Oswald, and L. Wil-son, J. Carbohydr. Chem. 6, 181 (1986).

  7. L. M. Kutrzeba, D. Ferreira, and J. K. Zjawjony, J. Nat. Prod. 72, 1361 (2009).

    Article  CAS  Google Scholar 

  8. G. Livingstone, F. Franks, and L. J. Aspinall, J. Solut. Chem. 6 (3), 203.

  9. M. Meng, M. Bagdasarian, and J. GregoryZeikus, Biochemistry 90, 8459 (1993).

    CAS  Google Scholar 

  10. Y. Wang, P. Wlodarczvk, A. P. Sokolov, and M. Paluch, J. Phys. Chem., 1475 (2013).

    Google Scholar 

  11. W. Bertil, Chirality 7, 350 (1993).

    Google Scholar 

  12. A. F. Casy, A. F. Drake, C. R. Ganellin, A. D. Mercer, and C. Upton, Chirality 4, 356 (1992).

    Article  CAS  Google Scholar 

  13. K. Fujimori, Macromol. Chem. Phys. 179, 625 (1978).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, Jankidevi Bajaj College of Science, Jamanalal Bajaj Marg, Civil Lines, Wardha, India

    S. D. Bajaj, P. V. Tekade & Manisha Chirde

Authors
  1. S. D. Bajaj
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. V. Tekade
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Manisha Chirde
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. D. Bajaj.

Additional information

The article is published in the original.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Bajaj, S.D., Tekade, P.V. & Chirde, M. Polarimetric study of rate constant for mutarotation of chiral levofloxacin, ofloxacin, sparfloxacin and ciprofloxacin drugs. Russ. J. Phys. Chem. B 9, 890–894 (2015). https://doi.org/10.1134/S1990793115060214

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1990793115060214

Keywords

Search

Navigation