Abstract
Pharmacological activity of echinochrome A (EchA) alone and in the biologically active additives (BAA) Timarin, administered per os has been investigated in volunteers. Blood hematological, immunological, and biochemical parameters were investigated before and after administration of the substances used. EchA decreased serum glutatione (GSH) and increased catalase activity 1 h after treatment. Later (3 h after administration) catalase activity normalized, while GSH exceeded the initial level. Changes in blood lipids suggest decreased risk of atherogenesis. Changes found in blood sex hormone levels indicate that Timarin may influence sex gland functioning. Changes of hematological and immunological parameters have been interpreted as the result of a mild stressor effect of both EchA alone and in the BAA Timarin increasing adaptation reactivity of the body.
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Original Russian Text © A.A. Artyukov, A.M. Popov, A.V. Tsybulsky, O.N. Krivoshapko, N.V. Polyakova, 2013, published in Biomeditsinskaya Khimiya.
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Artyukov, A.A., Popov, A.M., Tsybulsky, A.V. et al. Pharmacological activity of echinochrome a alone and in the biologically active additive Timarin. Biochem. Moscow Suppl. Ser. B 7, 237–242 (2013). https://doi.org/10.1134/S1990750813030025
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DOI: https://doi.org/10.1134/S1990750813030025