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Inclusion membrane proteins of Chlamydiaceae

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Abstract

Inclusion membrane proteins (Inc-proteins) belong to the family of unique chlamydial proteins. Members of this family attract attention of scientists because Inc-proteins are localized in the inclusion membrane, they have been found in all chlamydial species, expression of the most part of their genes begins during the first hours after the infection of cell culture. Biological functions of Inc-proteins remain unknown, but these proteins are suggested to play a key role in process of the development of the chlamydial infection.

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References

  1. Hackstadt, T., Curr. Opin. Microbiol., 1998, vol. 1, pp. 82–87.

    Article  CAS  Google Scholar 

  2. Hackstadt, T., Traffic., 2000, vol. 1, pp. 93–99.

    Article  CAS  Google Scholar 

  3. Salcedo, S.P. and Holden, D.W., Curr. Opin. Microbiol., 2005, vol. 8, pp. 92–98.

    Article  CAS  Google Scholar 

  4. Peeleng, R.W. and Brunham, R.C., Emerg. Infect. Dis., 1996, vol. 2, pp. 307–319.

    Google Scholar 

  5. Schachter, J., Sex Transm. Dis., 1999, vol. 26, pp. 279–280.

    Article  CAS  Google Scholar 

  6. Moulder, J.W., Microbiol. Rev., 1991, vol. 55, pp. 143–190.

    CAS  Google Scholar 

  7. Stephens, R.S., Kalman, S., Lammel, C., Fan, J., Marathe, R., Aravind, L., Mitchell, W., Olinger, L., Tatusov, R.L., Zhao, Q., Koonin, E.V., and Davis, R.W., Science, 1998, vol. 282, pp. 754–759.

    Article  CAS  Google Scholar 

  8. Wyrick, P.B., Cell. Microbiol., 2000, vol. 2, pp. 275–282.

    Article  CAS  Google Scholar 

  9. Fields, K.A. and Hackstadt, T., Annu. Rev. Cell Dev. Biol., 2002, vol. 18, pp. 221–245.

    Article  CAS  Google Scholar 

  10. Heinzen, R.A., Scidmore, M.A., Rockey, D.D., and Hackstadt, T., Infect. Immun., 1996, vol. 64, pp. 796–809.

    CAS  Google Scholar 

  11. Garcia-del Portillo, F., Zwick, M.B., Leung, K.Y., and Finlay, B.B., Proc. Natl. Acad. Sci. USA, 1993, vol. 90, pp. 10544–10548.

    Article  CAS  Google Scholar 

  12. Sturgill-Koszycki, S., Schaible, U.E., and Russell, D.G., EMBO J., 1996, vol. 15, pp. 6960–6968.

    CAS  Google Scholar 

  13. Mott, J., Barnewall, R.E., and Rikihisa, Y., Infect. Immun., 1999, vol. 67, pp. 1368–1378.

    CAS  Google Scholar 

  14. Lang, T., Hellio, R., Kaye, P.M., and Antoine, J.C., J. Cell Sci., 1994, vol. 107, pp. 2137–2150.

    CAS  Google Scholar 

  15. Swanson, M.S. and Isberg, R.R., Infect. Immun., 1995, vol. 63, pp. 3609–3620.

    CAS  Google Scholar 

  16. Pizarro-Cerda, J., Meresse, S., Parton, R.G., van der Goot, G., Sola-Landa, A., Lopez-Goni, I., Moreno, E., and Gorvel, J.P., Infect. Immun., 1998, vol. 66, pp. 5711–5724.

    CAS  Google Scholar 

  17. Heinzen, R.A. and Hackstadt, T., Infect. Immun., 1997, vol. 65, pp. 1088–1094.

    CAS  Google Scholar 

  18. Grieshaber, S., Swanson, J.A., and Hackstadt, T., Cell. Microbiol., 2002, vol. 4, pp. 273–284.

    Article  CAS  Google Scholar 

  19. Kiviat, N.B., Paavonen, J.A., Brockway, J., Critchlow, C.W., Brunham, R.C., Stevens, C.E., Stamm, W.E., Kuo, C.C., DeRouen, T., and Holmes, K.K., JAMA, 1985, vol. 253, pp. 989–996.

    Article  CAS  Google Scholar 

  20. Zhong, G., Fan, P., Ji, H., Dong, F., and Huang, Y., J. Exp. Med., 2001, vol. 193, pp. 935–942.

    Article  CAS  Google Scholar 

  21. Clifton, D.R., Fields, K.A., Grieshaber, S.S., Dooley, C.A., Fischer, E.R., Mead, D.J., Carabeo, R.A., and Hackstadt, T., PNAS, 2004, vol. 101, pp. 10166–10171.

    Article  CAS  Google Scholar 

  22. Subtil, A., Deievoye, C., Balana, M.-E., Tastevin, L., Perrinet, S., and Dautry-Varsat, A., Mol. Microbiol., 2005, vol. 56, pp. 1636–1647.

    Article  CAS  Google Scholar 

  23. Carlson, J.H., Porcella, S.F., McClarty, G., and Caldwell, H.D., Infect. Immun., 2005, vol. 73, pp. 6407–6418.

    Article  CAS  Google Scholar 

  24. Read, T.D., Brunham, R.C., Shen, C., Gill, S.R., Heidelberg, J.F., and White, O., Nucleic Acids Res., 2000, vol. 28, pp. 1397–1406.

    Article  CAS  Google Scholar 

  25. Kalman, S., Mitchell, W., Marathe, R., Lammel, C., Fan, J., Hyman, R.W., Olinger, L., Grimwood, J., Davis, R.W., and Stephens, R.S., Nat. Genet., 1999, vol. 21, pp. 385–389.

    Article  CAS  Google Scholar 

  26. Shirai, M., Hirakawa, H., Kimoto, M., Tabuchi, M., Kishi, F., Ouchi, K., Shiba, T., Ishii, K., Hattori, M., Kuhara, S., and Nakazawa, T., Nucleic Acids Res., 2000, vol. 28, pp. 2311–2314.

    Article  CAS  Google Scholar 

  27. Read, T.D., Myers, G.S., Brunham, R.C., Nelson, W.C., Paulsen, I.T., Heidelberg, J., Holtzapple, E., Khouri, H., Federova, N.B., Carty, H.A., Umayam, L.A., Haft, D.H., Peterson, J., Beanan, M.J., White, O., Salzberg, S.L., Hsia, R.C., McClarty, G., Rank, R.G., Bavoil, P.M., and Fraser, C.M., Nucleic. Acids Res., 2003, vol. 31, pp. 2134–2147.

    Article  CAS  Google Scholar 

  28. Rockey, D.D. and Rosquist, J.L., Infect. Immun., 1994, vol. 62, pp. 106–112.

    CAS  Google Scholar 

  29. Rockey, D.D., Heinzen, R.A., and Hackstadt, T., Mol. Microbiol., 1995, vol. 15, pp. 617–626.

    Article  CAS  Google Scholar 

  30. Bannantine, J.P., Rockey, D.D., and Hackstadt, T., Mol. Microbiol., 1998, vol. 28, pp. 1017–1026.

    Article  CAS  Google Scholar 

  31. Bannantine, J.P., Stamm, W.E., Suchland, R.J., and Rockey, D.D., Infect. Immun., 1998, vol. 66, pp. 6017–6021.

    CAS  Google Scholar 

  32. Bannantine, J.P., Griffiths, R.S., Viratyosin, W., Brown, W.J., and Rockey, D.D., Cell. Microbiol., 1999, vol. 2, pp. 35–47.

    Article  Google Scholar 

  33. Scidmore-Carlson, M.A., Shaw, E.I., Dooley, C.A., Fischer, E.R., and Hackstadt, T., Mol. Microbiol., 1999, vol. 33, pp. 753–765.

    Article  CAS  Google Scholar 

  34. Shaw, E.I., Dooley, C.A., Fischer, E.R., Scidmore, M.A., Fields, K.A., and Hackstadt, T., Mol. Microbiol., 2000, vol. 37, pp. 913–925.

    Article  CAS  Google Scholar 

  35. Giles, D.K., Whittimore, J.D., LaRue, R.W., Raulston, J.E., and Wyrick, P.B., Microbes Infect., 2006, vol. 8, pp. 1579–1591.

    Article  CAS  Google Scholar 

  36. Sisko, J.L., Spaeth, K., Kumar, Y., and Valdivia, R.H., Mol. Microbiol., 2006, vol. 60, pp. 51–66.

    Article  CAS  Google Scholar 

  37. Rockey, D.D., Grosenbach, D., Hruby, D.E., Peacock, M.G., Heinzen, R.A., and Hackstadt, T., Mol. Microbiol., 1997, vol. 24, pp. 217–228.

    Article  CAS  Google Scholar 

  38. Hackstadt, T., Scidmore-Carlson, M.A., Shaw, E.I., and Fischer, E.R., Cell. Microbiol., 1999, vol. 1, pp. 119–130.

    Article  CAS  Google Scholar 

  39. Scidmore, M.A. and Hackstadt, T., Mol. Microbiol., 2001, vol. 39, pp. 1638–1650.

    Article  CAS  Google Scholar 

  40. Toh, H., Miura, K., Shirai, M., and Hattori, M., DNA Research, 2003, vol. 10, pp. 9–17.

    Article  CAS  Google Scholar 

  41. Belland, R.J., Zhong, G., Crane, D.D., Hogan, D., Sturdevant, D., Sharma, J., Beatty, W.L., and Caldwell, H.D., Proc. Natl. Acad. Sci. USA, 2003, vol. 100, pp. 8478–8483.

    Article  CAS  Google Scholar 

  42. Nicholson, T.L., Olinger, L., Chong, K., Schoolnik, G., Stephens, R.S., J. Bacteriol., 2003, vol. 185, pp. 3179–3189.

    Article  CAS  Google Scholar 

  43. Subtil, A., Blocker, A., and Dautry-Varsat, A., Microbes Infect., 2000, vol. 2, pp. 367–369.

    Article  CAS  Google Scholar 

  44. Hsia, R.C., Pannekoek, Y., Ingerowski, E., and Bavoil, P.M., Mol. Microbiol., 1997, vol. 25, pp. 351–359.

    Article  CAS  Google Scholar 

  45. Bavoil, P.M. and Hsia, R., Mol. Microbiol., 1998, vol. 28, pp. 859–862.

    Article  Google Scholar 

  46. Fields, K.A., Mead, D.J., Dooley, C.A., and Hackstadt, T., Mol. Microbiol., 2003, vol. 48, pp. 671–683.

    Article  CAS  Google Scholar 

  47. Hueck C.J., Microbiol. Mol. Biol. Rev., 1998, vol. 62, pp. 379–433.

    CAS  Google Scholar 

  48. Wattiau, P., Bernier, B., Desle, P., Michiel, T., and Cornelis, G.R., Proc. Natl. Acad. Sci. USA, 1994, vol. 91, pp. 10493–10497.

    Article  CAS  Google Scholar 

  49. Anderson, D.M., Fouts, D.E., Collmer, A., and Schneewind, O., Proc. Natl. Acad. Sci. USA, 1999, vol. 96, pp. 12839–12843.

    Article  CAS  Google Scholar 

  50. Anderson, D.M. and Schneewind, O., Science, 1997, vol. 278, pp. 1140–1143.

    Article  CAS  Google Scholar 

  51. Rosqvist, R., Hakansson, S., Forsberg, A., and Wolf-Watz, H., EMBO J., 1995, vol. 14, pp. 4187–4195.

    CAS  Google Scholar 

  52. Frithz-Lindsten, E., Du, Y., Rosqvist, R., and Forsberg, A., Mol. Microbiol., 1997, vol. 25, pp. 1125–1139.

    Article  CAS  Google Scholar 

  53. Anderson, D.M., and Schneewind, O., Mol. Microbiol., 1999, vol. 31, pp. 1139–1148.

    Article  CAS  Google Scholar 

  54. Subtil, A., Parsot, C., and Dautry-Varsat, A., Mol. Microbiol., 2001, vol. 39, pp. 792–800.

    Article  CAS  Google Scholar 

  55. Menard, R., Sansonetti, P.J., and Parsot, C., J. Bacteriol., 1993, vol. 175, pp. 5899–5906.

    CAS  Google Scholar 

  56. Muschiol, S., Bailey, L., Gylfe, A., Sundin, C., Hultenby, K., Bergstrom, S., Elofsson, M., Wolf-Watz, H., Normark, S., and Henriques-Normark, B., Proc. Natl. Acad. Sci. USA, 2006, vol. 103, pp. 14566–14571.

    Article  CAS  Google Scholar 

  57. Fields, K.A., and Hackstadt, T., Mol. Microbiol., 2000, vol. 38, pp. 1048–1060.

    Article  CAS  Google Scholar 

  58. Ho, T.D. and Starnbach, M.N., Infect. Immun., 2005, vol. 73, pp. 905–911.

    Article  CAS  Google Scholar 

  59. Slepenkin, A., Motin, V., de la Maza, L.M., and Peterson, E.M., J. Bacteriol., 2005, vol. 187, pp. 473–479.

    Article  CAS  Google Scholar 

  60. Kostryukova, E.S., Lazarev, V.N., Titova, G.A., Akopian, T.A., Levitskii, and Govorun, V.M., Biochemistry (Moscow), 2006, vol. 71, pp. 333–340.

    Google Scholar 

  61. Rzomp, K.A., Moorhead, A.R., and Scidmore, M.A., Infect. Immun., 2006, vol. 74, pp. 5362–5373.

    Article  CAS  Google Scholar 

  62. Kostryukova, E.S., Korobova, F.V., Lazarev, V.N., Shkarupeta, M.M., Titova, G.A., Akopian, T.A., and Govorun, V.M., Byull. Eksper. Biol. Med., 2005, vol. 139, pp. 562–567.

    Article  CAS  Google Scholar 

  63. Delevoye, C., Nilges, M., Dautry-Varsat, A., and Subtil, A., J. Biol. Chem., 2004, vol. 279, pp. 46896–46906.

    Article  CAS  Google Scholar 

  64. Fasshauer, D., Sutton, R.B., Brunger, A.T., and Jahn, R., Proc. Natl. Acad. Sci. USA, 1998, vol. 95, pp. 15781–15786.

    Article  CAS  Google Scholar 

  65. Blyth, W.A. and Taverne, J., J. Hyg., 1972, vol. 70, pp. 33–37.

    Article  CAS  Google Scholar 

  66. Ridderhof, J.C. and Barnes, R.C., Infect. Immun., 1989, vol. 57, pp. 3189–3193.

    CAS  Google Scholar 

  67. Van Ooij, C., Homola, E., Kincaid, E., and Engel, J., Infect. Immun., 1998, vol. 66, pp. 5364–5371.

    Google Scholar 

  68. Rockey, D.D., Fischer, E.R., and Hackstadt, T., Infect. Immun., 1996, vol. 64, pp. 4269–4278.

    CAS  Google Scholar 

  69. Fields, K.A., Fischer, E.R., and Hackstadt, T., Infect. Immun., 2002, vol. 70, pp. 3816–3823.

    Article  CAS  Google Scholar 

  70. Rockey, D.D., Viratyosin, W., Bannantine, J.P., Suchland, R.J., and Stamm, W.E., Microbiology, 2002, vol. 148, pp. 2497–2505.

    CAS  Google Scholar 

  71. Suchland, R.J., Rockey, D.D., Bannantine, J.P., and Stamm, W.E., Infect. Immun., 2000, vol. 68, pp. 360–367.

    CAS  Google Scholar 

  72. Pannekoek, Y., van der Ende, A., Eijk, P.P., van Marle, J., de Witte, M.A., Ossewaarde, J.M., van den Brule, A.J., Morre, S.A., and Dankert, J., Infect. Immun., 2001, vol. 69, pp. 4654–4656.

    Article  CAS  Google Scholar 

  73. Geisler, W.M., Suchland, R.J., Rockey, D.D., and Stamm, W.E., J. Infect. Dis., 2001, vol. 184, pp. 879–884.

    Article  CAS  Google Scholar 

  74. Pannekoek, Y., Spaargaren, J., Langerak, A.A., Merks, J., Morre, S.A., and van der Ende, A., J. Clin. Microbiol., 2005, vol. 43, pp. 2441–2443.

    Article  CAS  Google Scholar 

  75. Alzhanov, D., Barnes, J., Hruby, D.E., and Rockey, D.D., BMC Microbiol., 2004, vol. 4, pp. 24–29.

    Article  CAS  Google Scholar 

  76. Fu, H., Subramanian, R.R., and Masters, S.C., Annu. Rev. Pharmacol. Toxicol., 2000, vol. 40, pp. 617–647.

    Article  CAS  Google Scholar 

  77. Fantl, W.J., Muslin, A.J., Kikuchi, A., Martin, J.A., Mac-Nicol, A.M., Gross, R.W., and Williams, L.T., Nature, 1994, vol. 371, pp. 612–614.

    Article  CAS  Google Scholar 

  78. Thorson, J.A., Yu, L.W.K., Hsu, A.L., Shih, N.-Y., Graves, P.R., and Tanner, J.W., Mol. Cell. Biol., 1998, vol. 18, pp. 5229–5238.

    CAS  Google Scholar 

  79. Meller, N., Liu, Y.-C., Collins, T.L., Bonnefoy-Berard, N., Baier, G., Isakov, N., and Altman, A., Mol. Cell. Biol., 1996, vol. 16, pp. 5782–5791.

    CAS  Google Scholar 

  80. Banik, U., Wang, G.-A., Wagner, P.D., and Kaufman, S., J. Biol. Chem., 1997, vol. 272, pp. 26219–26255.

    Article  CAS  Google Scholar 

  81. Gelperin, D., Weigle, J., Nelson, K., Roseboom, R., Irie, K., Matsumoto, K., and Lemmon, S., Proc. Natl. Acad. Sci. USA, 1995, vol. 92, pp. 11539–11543.

    Article  CAS  Google Scholar 

  82. Rzomp, K.A., Scholtes, L.D., Briggs, B.J., Whittaker, G.R., and Scidmore, M.A., Infect. Immun., 2003, vol. 71, pp. 5855–5870.

    Article  CAS  Google Scholar 

  83. Grieshaber, S.S., Grieshaber, N.A., and Hackstadt, T., J. Cell Sci., 2003, vol. 116, pp. 3793–3802.

    Article  CAS  Google Scholar 

  84. Bielli, A., Thornquist, P.O., Hendrick, A.G., Finn, R., Fitzgerald, K., and McCaffrey, M.W., Biochem. Biophys. Res. Commun., 2001, vol. 281, pp. 1141–1153.

    Article  CAS  Google Scholar 

  85. Starnbach, M.N., Bevan, M.J., and Lampe, M.F., J. Immunol., 1994, vol. 153, pp. 5183–5189.

    CAS  Google Scholar 

  86. Mu, F.T., Callaghan, J.M., Steele-Mortimer, O., Stenmark, H., Parton, R.G., Campbell, P.L., McCluskey, J., Yeo, J.P., Tock, E.P., and Toh, B.H., J. Biol. Chem., 1995, vol. 270, pp. 13503–13511.

    Article  CAS  Google Scholar 

  87. Christoforidis, S., McBride, H.M., Burgoyne, R.D., and Zerial, M., Nature, 1999, vol. 397, pp. 621–625.

    Article  CAS  Google Scholar 

  88. Dong, F., Su, H., Huang, Y., Zhong, Y., and Zhong, G., Infect. Immun., 2004, vol. 72, pp. 3863–3868.

    Article  CAS  Google Scholar 

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  1. Research Institute for Physico-Chemical Medicine, Ministry of Health and Social Development of the Russian Federation, ul. Malaya Pirogovskaya la, Moscow, 119992, Russia

    E. S. Kostryukova, V. N. Lazarev & V. M. Govorum

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  1. E. S. Kostryukova
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  2. V. N. Lazarev
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Original Russian Text © E.S. Kostryukova, V.N. Lazarev, V.M. Govorun, 2008, published in Biomeditsinskaya Khimiya.

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Kostryukova, E.S., Lazarev, V.N. & Govorum, V.M. Inclusion membrane proteins of Chlamydiaceae . Biochem. Moscow Suppl. Ser. B 2, 148–159 (2008). https://doi.org/10.1134/S1990750808020042

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