The specific features of free-radical processes and the antioxidant defense in the adult brain

Abstract

Here we review the specific features of free-radical processes in the CNS. We review the pathways of the generation of reactive oxygen species in nervous nerve tissue, the specific parameters of substrates of free-radical oxidation, and the contents and activities of various antioxidants. We briefly describe some physiological effects of reactive oxygen species in the nervous tissue.

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Correspondence to O. V. Galkina.

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Original Russian Text © O.V. Galkina, 2013, published in Neirokhimiya, 2013, Vol. 30, No. 2, pp. 93–102.

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Galkina, O.V. The specific features of free-radical processes and the antioxidant defense in the adult brain. Neurochem. J. 7, 89–97 (2013). https://doi.org/10.1134/S1819712413020025

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Keywords

  • free radicals
  • free-radical oxidation
  • antioxidant system, antioxidant defense
  • low molecular antioxidants
  • CNS
  • brain