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PEGylated Systems in Pharmaceutics

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Abstract

This review addresses the use of poly(ethylene glycol) (PEG) and PEG conjugation for the design of novel dosage forms and the modification of biomolecules. The peculiarities of PEGylated nanoparticles, liposomes, proteins, enzymes, and small drug and polyelectrolyte molecules and their influence on systemic drug delivery, including overcoming of various biological barriers and adhesion to mucosal tissues (mucoadhesion), are considered.

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Authors and Affiliations

  1. Institute of Pharmacy, Kazan State Medical University, 420126, Kazan, Tatarstan, Russia

    N. N. Porfiryeva, R. I. Moustafine & V. V. Khutoryanskiy

  2. Reading School of Pharmacy, University of Reading, RG66AD, Whiteknights, Reading, United Kingdom

    V. V. Khutoryanskiy

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  1. N. N. Porfiryeva
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  2. R. I. Moustafine
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  3. V. V. Khutoryanskiy
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Correspondence to R. I. Moustafine or V. V. Khutoryanskiy.

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Porfiryeva, N.N., Moustafine, R.I. & Khutoryanskiy, V.V. PEGylated Systems in Pharmaceutics. Polym. Sci. Ser. C 62, 62–74 (2020). https://doi.org/10.1134/S181123822001004X

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  • DOI: https://doi.org/10.1134/S181123822001004X

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