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To the Academician Alexander Spirin 90th Anniversary from Informosomes to the World of mRNP

Abstract

The main stages and achievements in the investigation of the fate of mRNA in eukaryotic cells, which began half a century ago with the discovery of informosomes by A.S. Spirin, there are discussed. The results of even the most recent studies confirm Spirin’s hypotheses about the structure and function of the informosomes, now called mRNPs. In the bibliography, we present only small part of the published articles in this field. The full list is too large.

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Correspondence to A. S. Voronina.

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The authors declare no conflicts of interest. This article does not contain any research involving humans or the use of animals as objects.

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Translated by M. Batrukova

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Voronina, A.S., Pshennikova, E.S. To the Academician Alexander Spirin 90th Anniversary from Informosomes to the World of mRNP. Dokl Biochem Biophys 499, 203–206 (2021). https://doi.org/10.1134/S1607672921040177

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Keywords:

  • mRNA
  • RNA-binding proteins
  • heavy informosomes
  • translation regulation