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Doklady Biochemistry and Biophysics

, Volume 478, Issue 1, pp 37–40 | Cite as

Messenger RNA of the Histidine-Rich Glycoprotein in Breast Tumors

  • A. I. Autenshlyus
  • I. I. Brusentsov
  • I. O. Marinkin
  • S. A. Smirnova
  • M. Yu. Rukavishnikov
  • V. V. Lyakhovich
Biochemistry, Biophysics, and Molecular Biology
  • 28 Downloads

Abstract

The content of mRNA of the histidine-rich glycoprotein (HRG), a potential marker of malignant neoplasia, which can be used in differential diagnosis of breast tumors, was determined in 110 breast tumor biopsy samples. The presence of HRG mRNA did not depend on the cancer type, on the preoperative treatment or its absence, as well as on the tumor progression stage and the presence of metastases.

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • A. I. Autenshlyus
    • 1
    • 2
  • I. I. Brusentsov
    • 1
    • 3
  • I. O. Marinkin
    • 1
  • S. A. Smirnova
    • 4
  • M. Yu. Rukavishnikov
    • 4
  • V. V. Lyakhovich
    • 2
  1. 1.Ministry of Healthcare of the Russian FederationNovosibirsk State Medical UniversityNovosibirskRussia
  2. 2.Research Institute of Molecular Biology and BiophysicsNovosibirskRussia
  3. 3.Federal Research Center Institute of Cytology and Genetics, Siberian BranchRussian Academy of SciencesNovosibirskRussia
  4. 4.JSC Vector-BestKol’tsovo, Novosibirsk oblastRussia

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