Abstract
A new mathematical method was used for the first time to search for tandem repeats with insertions and deletions in the full-length sequence of the A. thaliana genome. The method is based on a new algorithm for multiple alignment of sequences of certain periods without using paired comparisons of sequences. We identified 13997 periodic sites 2 to 50 characters long, only approximately 30% of which were known earlier. The possible origin and use of the identified sites with tandem repeats are discussed.
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References
Ulloa, M., Crop Sci., 2005, vols. 1–2.
Durbin, R., Eddy, S.R., Krogh, A., and Mitchison, G., Cambridge: Cambridge University Press, 1998.
Suvorova, Y.M., Korotkova, M.A., and Korotkov, E.V., Comput. Biol. Chem., 2014, vol. 53, pp. 43–48.
Holste, D., Grosse, I., Beirer, S., Schieg, S., and Herzel, H., Phys. Rev. E, 2003, vol. 67, p. 61913.
Benson, G., Nucleic Acids Res., 1999, vol. 27, no. 2, pp. 573–580.
Pugacheva, V., Korotkov, A., and Korotkov, E., Stat. Appl. Genet. Mol. Biol., 2016, vol. 15, no. 5, pp. 381–400.
Frenkel, F.E., Korotkova, M.A., and Korotkov, E.V., Biomed. Res. Int., 2017, vol. 2017, pp. 1–9.
Frenkel, F.E. and Korotkov, E.V., Gene, 2008, vol. 421, nos. 1–2, pp. 52–60.
Jorda, J. and Kajava, A.V., Bioinformatics, 2009, vol. 25, no. 20, pp. 2632–8.
Herzel, H., Weiss, O., and Trifonov, E.N., Bioinformatics, 1999, vol. 15, no. 3, pp. 187–193.
Kadauke, S. and Blobel, G.A., Biochim. Biophys. Acta, 2009, vol. 1789, no. 1, pp. 17–25.
Richard, G.F., Kerrest, A., and Dujon, B., Microbiol. Mol. Biol. Rev., 2008, vol. 72, no. 4, pp. 686–727.
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Original Russian Text © E.V. Korotkov, Yu.M. Suvorova, K.G. Skryabin, 2017, published in Doklady Akademii Nauk, 2017, Vol. 477, No. 6, pp. 742–744.
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Korotkov, E.V., Suvorova, Y.M. & Skryabin, K.G. Search of tandem repeats with insertion and deletions in the A. thaliana genome. Dokl Biochem Biophys 477, 398–400 (2017). https://doi.org/10.1134/S160767291706014X
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DOI: https://doi.org/10.1134/S160767291706014X