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MicroRNA in hormonal mechanisms of regulation of NK cell function

  • Biochemistry, Biophysics, and Molecular Biology
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Abstract

We investigated the effect of human chorionic gonadotropin, estriol, leptin, ghrelin, and kisspeptin on the microRNA expression in separated NK cells. All of these hormones are able to effectively modulate the expression of microRNAs both stimulating and suppressing the cytotoxic potential of NK cells and thereby indirectly regulate the functions of these lymphocytes.

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Authors and Affiliations

  1. Institute of Ecology and Genetics of Microorganisms, Ural Department, Russian Academy of Science, Perm, 614081, Russia

    S. V. Shirshev, I. V. Nekrasova, O. L. Gorbunova, E. G. Orlova & I. L. Maslennikova

Authors
  1. S. V. Shirshev
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  2. I. V. Nekrasova
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  3. O. L. Gorbunova
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  4. E. G. Orlova
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  5. I. L. Maslennikova
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Corresponding author

Correspondence to I. V. Nekrasova.

Additional information

Original Russian Text © S.V. Shirshev, I.V. Nekrasova, O.L. Gorbunova, E.G. Orlova, I.L. Maslennikova, 2017, published in Doklady Akademii Nauk, 2017, Vol. 474, No. 1, pp. 123–127.

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Shirshev, S.V., Nekrasova, I.V., Gorbunova, O.L. et al. MicroRNA in hormonal mechanisms of regulation of NK cell function. Dokl Biochem Biophys 474, 168–172 (2017). https://doi.org/10.1134/S160767291703005X

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  • DOI: https://doi.org/10.1134/S160767291703005X

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