Abstract
Narrowly dispersed hydrophilic block and random copolymers of acrylic acid and N-isopropylacrylamide of various compositions and molecular masses are synthesized for the first time by controlled radical polymerization via the reversible addition-fragmentation chain-transfer mechanism. The copolymers are used for the synthesis of ternary copolymers with n-butyl acrylate. As shown by dynamic light scattering, the resulting amphiphilic copolymers can form stable dispersions in diluted aqueous solutions. It is found that the effective hydrodynamic radii of dispersion particles may be controlled via variation both in the primary structure of the ternary copolymer, i.e., the amount and sequence of hydrophilic and hydrophobic units, and in the external stimuli, i.e., the temperature and pH of a solution.
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References
P. Ilg, Soft Matter 9, 3465 (2013).
D. E. Bergbreiter, B. L. Case, Y. S. Liu, and J. W. Caraway, Macromolecules 31, 6053 (1998).
L. D. Taylor and L. D. Cerankowski, J. Polym. Sci., Part A: Polym. Chem. 13, 2551 (1975).
L. Y. Zhang, R. Guo, M. Yang, X. Q. Jiang, and B. R. Liu, Adv. Mater. 19, 2988 (2007).
C. L. He, C. W. Zhao, X. S. Chen, Z. J. Guo, X. L. Zhuang, and X. B. Jing, Macromol. Rapid Commun 29, 490 (2008).
R. G. Sousa, A. Prior-Cabanillas, I. Quijada-Garrido, and J. M. Barrales-Rienda, J. Controlled Release 102, 595 (2005).
X. Yin, A. S. Hoffman, and P. S. Stayton, Biomacromolecules 7, 1381 (2006).
X. Gao, Y. Cao, X. Song, Z. Zhang, C. Xiao, C. He, and X. Chena, J. Mater. Chem. B 1, 5578 (2013).
A. Khan, J. Colloid Interface Sci. 313, 697 (2007).
H. Feil, Y. H. Bae, J. Feijen, and S. W. Kim, Macromolecules 26, 2496 (1993).
M. Bradley, J. Ramos, and B. Vincent, Langmuir 21, 1209 (2005).
M. Bradley and B. Vincent, Langmuir 21, 8630 (2005).
M. J. Snowden, B. Z. Chowdhry, B. Vincent, and G. E. Morris, J. Chem. Soc., Faraday Trans. 92, 5013 (1996).
D. E. Meyer, B. C. Shin, G. A. Kong, M. W. Dewhirst, and A. Chilkoti, J. Controlled Release 74, 213 (2001).
P. S. Stayton, A. S. Hoffman, N. Murthy, C. A. Lackey, C. Y. Cheung, P. Tan, L. A. Klumb, A. Chilkoti, and F. S. Wilbur, J. Controlled Release 65, 203 (2000).
X. Z. Zhang, Y. Y. Yang, F. J. Wang, and T. S. Chung, Langmuir 18, 2013 (2002).
S. J. Lue, C. H. Chen, and C. M. Shih, J. Macromol. Sci., Part B: Phys. 50, 563 (2011).
H. Kayi, S. A. Tuncel, A. Elkamel, and E. Alper, J. Mol. Model. 11, 55 (2005).
M. Nuopponen, J. Ojala, and H. Tenhu, Polymer 45, 3643 (2004).
K. Troll, A. Kulkarni, W. Wang, C. Darko, A. M. B. Koumba, and A. Laschewsky, Colloid Polym. Sci. 286, 1079 (2008).
J. Škvarla, J. Zednik, M. Šlouf, S. Pispas, and M. Štepánek, Eur. Polym. J. 61, 124 (2014).
H. H. Nguyen, M. El Ezzi, C. Mingotaud, M. Destarac, J.-D. Marty, and N. Lauth-De Viguerie, Soft Matter 12, 3246 (2016).
D. V. Vishnevetski, E. A. Lysenko, A. V. Plutalova, and E. V. Chernikova, Polym. Sci., Ser. A 58 (1), 1 (2016).
E. V. Chernikova, A. V. Plutalova, K. O. Mineeva, I. R. Nasimova, E. Yu. Kozhunova, A. V. Bol’shakova, A. V. Tolkachev, N. S. Serkhacheva, S. D. Zaitsev, N. I. Prokopov, and A. B. Zezin, Polym. Sci., Ser. B 57 (6), 547 (2015).
E. V. Chernikova, P. S. Terpugova, C. Bui, and B. Chlarleux, Polymer 44 (5), 4101 (2003).
L. Couvreur, C. Lefay, J. Belleney, B. Charleux, O. Guerret, and S. Magnet, Macromolecules 36, 8260 (2003).
E. V. Vasilyeva, N. A. Kopylova, S. D. Zaitsev, and Yu. D. Semchikov, Polym. Sci., Ser. B 53 (9–10), 491 (2011).
E. A. Egorova, V. P. Zubov, I. V. Bakeeva, E. V. Chernikova, and E. A. Litmanovich, Polym. Sci., Ser. A 55 (9–10), 519 (2013).
C. Ladaviure, N. Dörr and J. P. Claverie, Macromolecules 34 (16), 5370 (2001).
A. J. Convertine, N. Ayres, C. W. Scales, A. B. Lowe, C. L. McCormick, Biomacromolecules 5, 1177 (2004).
G. Moad, E. Rizzardo, and S. H. Thang, Polymer 49 (5), 1079 (2008).
Polymer Handbook, Ed. by J. Brandrup, E. H. Immergut, and E. A. Grulke (Wiley, New York, 1999).
V. A. Kabanov, V. P. Zubov, and Yu. D. Semchikov, Complex–Radical Polymerization (Khimiya, Moscow, 1987) [in Russian].
G. Saint, G. Polla-Mattiot, and M. Meirone, J. Polym. Sci. 50 (153), 12 (1961).
S. A. Pooley, B. L. Rivas, F. E. Lillo, C. Del, and G. Pizzaro, J. Chil. Chem. Soc 55 (1), 19 (2010).
E. V. Chernikova, A. V. Tarasenko, E. S. Garina, and V. B. Golubev, Polym. Sci., Ser. A 48 (10), 1046 (2006).
X. André, M. Zhang, and A. H. E. Müller, Macromol. Rapid Commun. 26, 558 (2005).
O. Colombani, M. Ruppel, F. Schubert, H. Zettl, D. V. Pergushov, and A. H. E. Müller, Macromolecules 40, 4338 (2007).
O. Colombani, M. Ruppel, M. Burkhardt, M. Drechsler, M. Schumacher, M. Gradzielski, R. Schweins, and A. H. E. Muller, Macromolecules 40, 4351 (2007).
L. M. Bronstein, D. M. Chernyshov, G. I. Timofeeva, L. V. Dubrovina, P. M. Valetsky, and A. R. Khokhlov, Langmuir 15, 6195 (1999).
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Original Russian Text © E.V. Chernikova, A.V. Plutalova, K.O. Mineeva, D.V. Vishnevetskii, E.A. Lysenko, N.S. Serkhacheva, N.I. Prokopov, 2016, published in Vysokomolekulyarnye Soedineniya, Seriya B, 2016, Vol. 58, No. 5, pp. 402–412.
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Chernikova, E.V., Plutalova, A.V., Mineeva, K.O. et al. Ternary copolymers of acrylic acid, N-isopropylacrylamide, and butyl acrylate: Synthesis and aggregative behavior in dilute solutions. Polym. Sci. Ser. B 58, 564–573 (2016). https://doi.org/10.1134/S1560090416050031
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DOI: https://doi.org/10.1134/S1560090416050031