Skip to main content
SpringerLink
Log in

Uniformity and Sensitivity Measurements for Small Field of View Pixelated SPECT System with Coded Aperture

  • RADIOBIOLOGY, ECOLOGY AND NUCLEAR MEDICINE
  • Published:
Physics of Particles and Nuclei Letters Aims and scope Submit manuscript

Abstract –

This paper describes the methodology and measurements results of the micro-SPECT system parameters with a 57 × 57 mm field of view. The system detection efficiency and uniformity of the Timepix based micro-SPECT system is measured using a 99mTc radioactive source. The system detection efficiency is 81%, while the total efficiency is 0.0038% only, mainly due to the small surface of the detector. The intrinsic uniformity is 92%. The integral and differential uniformity are 44 and 84%, respectively. The integral uniformity can be significantly improved by using additional filters and more advanced decoding algorithms that take into account the geometry of the collimator.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.

Similar content being viewed by others

REFERENCES

  1. M. A. Pysz, S. S. Gambhir, and J. K. Willmann, “Molecular imaging: Current status and emerging strategies,” Clin. Radiol. 65, 500–516 (2010).

    Article  Google Scholar 

  2. International Atomic Energy Agency, Planning a Clinical PET Centre, No. 11 of IAEA Human Health Series (IAEA, Vienna, Austria, 2010), p. 160.

  3. www.techstreet.com/nema/standards/nema-nu-1-2018? product_id=2073744.

  4. www.techstreet.com/nema/standards/nema-nu-2-2018? product_id=2017225.

  5. International Atomic Energy Agency, Quality Assurance for SPECT Systems, No. 6 of IAEA Human Health Series (IAEA, Vienna, Austria, 2009), p. 263.

  6. V. Rozhkov et al., “Visualization of radiotracers for SPECT imaging using a timepix detector with a coded aperture,” J. Instrum. 15 (06), P06028–P06028 (2020).

    Article  Google Scholar 

  7. X. Llopart, R. Ballabriga, M. Campbell, L. Tlustos, and W. Wong, “Timepix, a 65k programmable pixel readout chip for arrival time, energy and/or photon counting measurements,” Nucl. Instrum. Methods Phys. Res., Sect. A 581, 485-494 (2007).

    Google Scholar 

  8. A. Butler, P. Butler, S. Bell, G. A. Chelkov, et al., “Measurement of the energy resolution and calibration of hybrid pixel detectors with GaAs:Cr sensor and Timepix readout chip,” Phys. Part. Nucl. Lett. 12, 59–73 (2015).

    Article  Google Scholar 

  9. M. J. Cieślak, K. A. A. Gamage, and R. Glover, “Coded-aperture imaging systems: Past, present and future development—A review,” Rad. Meas. 92, 59–71 (2016).

    Article  Google Scholar 

  10. S. R. Gottesman and E. E. Fenimore, “New family of binary arrays for coded aperture imaging,” Appl. Opt. 28, 4344 (1989).

    Article  ADS  Google Scholar 

Download references

Funding

The reported study was funded jointly by Russian Foundation for Basic Research and Ministry of Science, Technology and Environment (Cuba), project no. 18-52-34005.

Author information

Authors and Affiliations

  1. Joint Institute for Nuclear Research, 141980, Dubna, Russia

    V. A. Rozhkov, A. S. Zhemchugov, A. Leyva & P. I. Smolyanskiy

  2. Center of Technological Applications and Nuclear Development, 11300, Havana, Cuba

    A. Leyva

Authors
  1. V. A. Rozhkov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. S. Zhemchugov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Leyva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. I. Smolyanskiy
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. A. Rozhkov.

Ethics declarations

The authors declare that they have no conflicts of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rozhkov, V.A., Zhemchugov, A.S., Leyva, A. et al. Uniformity and Sensitivity Measurements for Small Field of View Pixelated SPECT System with Coded Aperture. Phys. Part. Nuclei Lett. 19, 594–596 (2022). https://doi.org/10.1134/S1547477122050363

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1547477122050363

Search

Navigation