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Numerical modeling of magnetic drug targeting

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Abstract

A special focused magnet, designed for the use in the magnetic targeted drug delivery system, was constructed. The theoretical calculation of the adhesion condition for a magnetic fluid drop in magnetic field with obtained design showed that the constructed focused magnet generates a sufficient magnetic force for the capture of a magnetic drop on the vessel wall and can be used 1.5–2 cm deeper in an organism compared with the prism permanent magnet, which can enable non-invasivity of the magnetic drug targeting procedure. The maximal values for magnetic field and gradient of magnetic field are 0.38 T and 101 T/m, respectively.

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Authors and Affiliations

  1. Institute of Experimental Physics, Slovakia, Russia

    P. Kopcansky, M. Timko, M. Hnatic & M. Vala

  2. Joint Institute for Nuclear Research, Dubna, Russia

    M. Vala, G. M. Arzumanyan, E. A. Hayryan & L. Jancurova

  3. Technical University, Slovakia, Russia

    L. Jancurova & J. Jadlovsky

Authors
  1. P. Kopcansky
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  2. M. Timko
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  3. M. Hnatic
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  4. M. Vala
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  5. G. M. Arzumanyan
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  6. E. A. Hayryan
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  7. L. Jancurova
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  8. J. Jadlovsky
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Kopcansky, P., Timko, M., Hnatic, M. et al. Numerical modeling of magnetic drug targeting. Phys. Part. Nuclei Lett. 8, 502–505 (2011). https://doi.org/10.1134/S154747711105013X

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  • DOI: https://doi.org/10.1134/S154747711105013X

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