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Study of the Stability of Zeolites in Model Biological Environments

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Abstract

The stability of synthetic and natural zeolites in model biological media simulating the environment of the stomach (pH 1.8), blood plasma (pH 6.9), and intestines (pH 8) is studied. The effect of long-term exposure (up to 7 days) to biological media on the crystal structure of Beta, Rho, Y, and clinoptilolite zeolites is studied. The degree of degradation of the crystal structure of zeolites is controlled by X-ray phase analysis. Based on the results obtained, conclusions are drawn on the prospects for the use of synthetic and natural zeolites as drug carriers.

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Funding

This study was carried out as part of a state task of the Institute of Silicate Chemistry, Russian Academy of Sciences (subject no. 0081-2022-0001).

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  1. Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences, 199034, St. Petersburg, Russia

    N. Yu. Ul’yanova, E. Yu. Brazovskaya & O. Yu. Golubeva

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  1. N. Yu. Ul’yanova
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  2. E. Yu. Brazovskaya
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  3. O. Yu. Golubeva
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Correspondence to N. Yu. Ul’yanova.

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Ul’yanova, N.Y., Brazovskaya, E.Y. & Golubeva, O.Y. Study of the Stability of Zeolites in Model Biological Environments. Glass Phys Chem 49, 706–708 (2023). https://doi.org/10.1134/S1087659623600734

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  • DOI: https://doi.org/10.1134/S1087659623600734

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