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Onion (Allium cepa L.) Extract: A Green and Eco-friendly Catalyst for MW-Assisted Solvent-Free Synthesis of Pyrroles via Paal–Knorr Reaction

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Abstract

An environmentally friendly and highly efficient method for onion extract-catalyzed microwave-assisted solvent- free synthesis of pyrroles via Paal–Knorr reaction with hexane-2,5-dione has been developed. This method is applicable to a wide range of aromatic, aliphatic, and heterocyclic primary amines, and it affords various pyrrole derivatives in good to excellent yields (up to 98%) at 80°C. The use of onion extract as catalyst makes the process environmentally benign.

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This work was supported by ongoing institutional funding. No additional grants to carry out or direct this particular research were obtained.

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Authors and Affiliations

  1. Department of Chemistry, Payam Noor University, 193953697, Tehran, Iran

    O. Marvi

  2. Faculty of Chemical Engineering, University of Science & Technology of Mazandaran, 851878413, Behshahr, Iran

    S. Arshadi

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  1. O. Marvi
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  2. S. Arshadi
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Correspondence to O. Marvi.

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Marvi, O., Arshadi, S. Onion (Allium cepa L.) Extract: A Green and Eco-friendly Catalyst for MW-Assisted Solvent-Free Synthesis of Pyrroles via Paal–Knorr Reaction. Russ J Org Chem 60, 472–479 (2024). https://doi.org/10.1134/S1070428024030151

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