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Recyclization of 5-Aryl-1H-pyrrole-2,3-diones with Amidoximes. Synthesis of Enamines Containing a 1,2,4-Oxadiazole Fragment

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Abstract

5-Aryl-1H-pyrrole-2,3-diones reacted with amidoximes to give enamines containing a 1,2,4-oxadi­azole fragment that are potential precursors to novel 1H-pyrrole-2,3-diones. The described reaction is the first example of recyclization of 4-unsubstitued 5-aryl-1H-pyrrole-2,3-diones by the action of 1,4-binucleophiles.

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Funding

This study was performed under financial support by the Russian Foundation for Basic Research (project nos. 20-33-90264 and 20-43-596008), Perm Krai, and Ministry of Science and Higher Education of the Russian Federation (project no. FSNF-2023-0004).

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Authors and Affiliations

  1. Perm State University, 614068, Perm, Russia

    D. I. Antonov, M. V. Dmitriev, I. A. Kuchumov & A. N. Maslivets

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  1. D. I. Antonov
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  2. M. V. Dmitriev
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  3. I. A. Kuchumov
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  4. A. N. Maslivets
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Correspondence to A. N. Maslivets.

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Antonov, D.I., Dmitriev, M.V., Kuchumov, I.A. et al. Recyclization of 5-Aryl-1H-pyrrole-2,3-diones with Amidoximes. Synthesis of Enamines Containing a 1,2,4-Oxadiazole Fragment. Russ J Org Chem 60, 387–390 (2024). https://doi.org/10.1134/S1070428024030023

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