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Synthesis of New Polycyclic Adducts Derived from Tetraazadecalin

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Abstract

A one-pot synthesis of 4,9-dimethyl-2,3a,5a,7,8a,10a-hexaazaperhydropyrenes by the catalytic heterocyclization of 2,6-dimethyl-1,4,5,8-tetraazadecalin with a cyclomethylating reagent (formaldehyde or tetramethylmethanediamine) and substituted anilines.

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ACKNOWLEDGMENTS

Structural studies were carried out at the Agidel Center for Collective Use, Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences.

Funding

This work was supported by institutional funding for the research projects “Multicomponent catalytic reactions in the synthesis of cyclic and acyclic heteroatomic compounds” (FMRS-2022-0079) and “Natural and synthetic metabolites, study of the mechanisms of their action—promising drugs for medicine” (FMRS-2022-0074).

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Authors and Affiliations

  1. Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences, 450075, Ufa, Russia

    E. B. Rakhimova & V. Yu. Kirsanov

Authors
  1. E. B. Rakhimova
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  2. V. Yu. Kirsanov
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Correspondence to E. B. Rakhimova.

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The authors of this work declare that they have no conflicts of interest.

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Translated from Zhurnal Organicheskoi Khimii, 2023, Vol. 59, No. 11, pp. 1492–1496 https://doi.org/10.31857/S0514749223110113.

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Rakhimova, E.B., Kirsanov, V.Y. Synthesis of New Polycyclic Adducts Derived from Tetraazadecalin. Russ J Org Chem 59, 1990–1993 (2023). https://doi.org/10.1134/S1070428023110192

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  • DOI: https://doi.org/10.1134/S1070428023110192

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