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Application of the Knorr Reaction for the Directed Synthesis of Pyrazole Derivatives as Biologically Active Coligands for Gold Glyconanoparticles

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Abstract

The reaction of acetylacetone with 6-sulfanylhexanoic and 11-sulfanylundecanoic acid hydrazides was used to develop a method for the synthesis of previously unknown 1-(ω-sulfanylacyl)-3,5-dimethylpyrazoles as promising coligands for preparing gold glyconanoparticles for biomedical purposes.

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Funding

This work was supported by ongoing institutional funding. No additional grants to carry out or direct this particular research were obtained.

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Authors and Affiliations

  1. Institute of Macromolecular Compounds, Russian Academy of Sciences, 199004, St. Petersburg, Russia

    A. Y. Ershov & A. A. Martynenkov

  2. State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation, 195043, St. Petersburg, Russia

    I. V. Lagoda & A. A. Batyrenko

Authors
  1. A. Y. Ershov
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  2. A. A. Martynenkov
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  3. I. V. Lagoda
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  4. A. A. Batyrenko
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Correspondence to A. Y. Ershov.

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Translated from Zhurnal Organicheskoi Khimii, 2023, Vol. 59, No. 11, pp. 1489–1491 https://doi.org/10.31857/S0514749223110101.

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Ershov, A.Y., Martynenkov, A.A., Lagoda, I.V. et al. Application of the Knorr Reaction for the Directed Synthesis of Pyrazole Derivatives as Biologically Active Coligands for Gold Glyconanoparticles. Russ J Org Chem 59, 1988–1989 (2023). https://doi.org/10.1134/S1070428023110180

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  • DOI: https://doi.org/10.1134/S1070428023110180

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