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Silica-Zinc Chloride (SiO2-ZnCl2)-Mediated Facile Synthesis of Some Nitro-Substituted Arylimidazopyridine Analogs

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Abstract

Silica-zinc chloride (SiO2-ZnCl2)-mediated method has been developed for the synthesis of 2-nitro-3-arylimidazo[1,2-a]pyridine derivatives from 2-aminopyridines and β-nitrostyrenes. This new methodology offers operational simplicity, mild conditions, easy workup process, and good to excellent yields of various 3-aryl-2-nitroimidazo[1,2-a]pyridines.

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Authors and Affiliations

  1. Department of Chemistry, Acharya Nagarjuna University, 522510, Guntur, Andhra Pradesh, India

    A. V. Krishna & B. H. Babu

  2. Division of Forensic Chemistry, AP Forensic Science Laboratory, Mangalagiri, Andhra Pradesh, India

    A. V. Krishna

  3. Department of Nanotechnology, Acharya Nagarjuna University, 522510, Guntur, Andhra Pradesh, India

    B. H. Babu

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  1. A. V. Krishna
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Correspondence to B. H. Babu.

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Krishna, A.V., Babu, B.H. Silica-Zinc Chloride (SiO2-ZnCl2)-Mediated Facile Synthesis of Some Nitro-Substituted Arylimidazopyridine Analogs. Russ J Org Chem 59, 1192–1197 (2023). https://doi.org/10.1134/S1070428023070102

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