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Synthesis of 4,5-Dihydro-1,2-oxazoles and 1,2-Oxazole Containing Uracil Fragments

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Abstract

1,3-Dipolar cycloaddition of allylic compounds or propargyl alcohol to nitrile oxide generated from 6-methyluracil-5-carboximidoyl chloride afforded a series of 4,5-dihydro-1,2-oxazoles and 1,2-oxazole contain­ing uracil fragments.

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ACKNOWLEDGMENTS

The spectral studies were performed using the facilities of the Chemistry service center, Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences.

Funding

This study was financially supported in the framework of state assignment of the Ministry of Science and Higher Education of the Russian Federation (project no. 122031400260-7).

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Authors and Affiliations

  1. Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 450054, Ufa, Russia

    I. B. Chernikova, M. S. Yunusov & A. N. Lobov

Authors
  1. I. B. Chernikova
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  2. M. S. Yunusov
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  3. A. N. Lobov
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Correspondence to I. B. Chernikova.

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The authors declare the absence of conflict of interest.

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Chernikova, I.B., Yunusov, M.S. & Lobov, A.N. Synthesis of 4,5-Dihydro-1,2-oxazoles and 1,2-Oxazole Containing Uracil Fragments. Russ J Org Chem 59, 1078–1081 (2023). https://doi.org/10.1134/S1070428023060179

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  • DOI: https://doi.org/10.1134/S1070428023060179

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