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Simple One-Pot Synthesis of Novel 5-(3,5-Dialkyl-1H-pyrazol-1-yl)-2-ethoxy-1,4,2λ5-diazaphosphole 2-Oxides

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Abstract

A simple one-pot synthesis of novel 5-pyrazolyl-1,4,2-diazaphosphole derivatives is developed. The synthesis involves a three-component reaction of dimethyl (formamide/acetamide) dimethyl acetal or carbon disulfide with triethyl phosphite and 1H-pyrazole-1-carboximidamides in dioxane. The structure of the synthesized compounds was confirmed by spectral methods and elemental analysis.

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Funding

The authors extend their appreciation to the deanship of scientific research at King Khalid University for funding this work through the Research Groups Program (grant no. RGP.2/8/43).

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, King Khalid University, 61421, Abha, Saudi Arabia

    M. A. Assiri & T. E. Ali

  2. Department of Chemistry, Faculty of Education, Ain Shams University, 11711, Cairo, Egypt

    T. E. Ali

  3. Department of Chemistry, Faculty of Science and Arts, King Khalid University, 61435, Mohail, Saudi Arabia

    A. Y. Alzahrani & M. A. Salem

  4. Department of Chemistry, Faculty of Science, Al-Azhar University, 11884, Cairo, Egypt

    M. A. Salem

Authors
  1. M. A. Assiri
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  2. T. E. Ali
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  3. A. Y. Alzahrani
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  4. M. A. Salem
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Correspondence to T. E. Ali.

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Assiri, M.A., Ali, T.E., Alzahrani, A.Y. et al. Simple One-Pot Synthesis of Novel 5-(3,5-Dialkyl-1H-pyrazol-1-yl)-2-ethoxy-1,4,2λ5-diazaphosphole 2-Oxides. Russ J Org Chem 59, 285–289 (2023). https://doi.org/10.1134/S1070428023020094

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  • DOI: https://doi.org/10.1134/S1070428023020094

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