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Synthesis of Spiro(pyrrol-2,5'-pyrrolo[2,3-d]pyrimidine)-2',4',5,6'-tetraones by the Reaction of Pyrrolo[2,1-c][1,4]oxazinetriones with 6-Aminopyrimidine-2,4-diones

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Abstract

8-Aroyl-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,6,7-triones react with 6-aminopyrimidine-2,4(1H,3H)-diones to form 3-aroyl-4-hydroxy-1-(2-hydroxyalkyl)spiro(pyrrole-2,5'-pyrrolo[2,3-d]pyrimidine)-2',4',5,6'(1H,1'H,3'H,7'H)-tetraones. The structure of the products was confirmed by X-ray diffraction analysis.

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Funding

The research was financially supported by the “Rational Subsoil Use 2023” Perm Scientific and Educational Center. The XRD analysis was carried out with the support of the Ministry of Education and Science of the Russian Federation (project no. FSNF-2023-0004).

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Authors and Affiliations

  1. Perm State University, 614990, Perm, Russia

    N. A. Tretyakov, M. V. Dmitriev & A. N. Maslivets

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  1. N. A. Tretyakov
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  2. M. V. Dmitriev
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  3. A. N. Maslivets
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Correspondence to A. N. Maslivets.

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The authors declare no conflict of interest.

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Translated from Zhurnal Organicheskoi Khimii, 2023, Vol. 59, No. 2, pp. 180–186 https://doi.org/10.31857/S0514749223020039.

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Tretyakov, N.A., Dmitriev, M.V. & Maslivets, A.N. Synthesis of Spiro(pyrrol-2,5'-pyrrolo[2,3-d]pyrimidine)-2',4',5,6'-tetraones by the Reaction of Pyrrolo[2,1-c][1,4]oxazinetriones with 6-Aminopyrimidine-2,4-diones. Russ J Org Chem 59, 237–242 (2023). https://doi.org/10.1134/S1070428023020033

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