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Synthesis of New Isoquinoline Derivatives from the Condensation Products of Acid Anhydrides and 2-(3,4-Dimethoxyphenyl)ethanamine

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Abstract

A simple and convenient method has been proposed for the synthesis of new isoquinoline derivatives via intramolecular cyclization of imides obtained from acid anhydrides and 2-(3,4-dimethoxyphenyl)ethanamine (homoveratrylamine). The cyclization was carried out by treatment with sodium tetrahydridoborate and aqueous hydrogen chloride.

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ACKNOWLEDGMENTS

This study was performed using the facilities of the Chemistry joint center, Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences.

Funding

This study was financially supported by state assignment no. 122031400278-2.

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Authors and Affiliations

  1. Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 450054, Ufa, Russia

    I. M. Sakhautdinov, G. F. Sakhautdinova, M. F. Abdullin, T. R. Nugumanov & A. G. Mustafin

  2. Research Institute of Chemical Diversity, Khimki, 141401, Moscow oblast, Russia

    R. N. Malikova

Authors
  1. I. M. Sakhautdinov
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  2. R. N. Malikova
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  3. G. F. Sakhautdinova
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  4. M. F. Abdullin
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  5. T. R. Nugumanov
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  6. A. G. Mustafin
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Corresponding author

Correspondence to I. M. Sakhautdinov.

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Sakhautdinov, I.M., Malikova, R.N., Sakhautdinova, G.F. et al. Synthesis of New Isoquinoline Derivatives from the Condensation Products of Acid Anhydrides and 2-(3,4-Dimethoxyphenyl)ethanamine. Russ J Org Chem 58, 1984–1988 (2022). https://doi.org/10.1134/S1070428022120302

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  • DOI: https://doi.org/10.1134/S1070428022120302

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