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Synthesis of (3S,4S)-4-Acetyl-3-(1R)-1-hydroxyethyl-1-(4-methoxyphenyl)azetidin-2-one

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Abstract

The synthesis of the title compound from l-threonine with the participation of β-methallyl chloride amide in the N-alkylation step is described.

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ACKNOWLEDGMENTS

Analyses were performed on the equipment of the Khimiya Center for Collective Use, Ufa Institute of Chemistry, Russian Academy of Sciences.

Funding

The work was performed according to the state assignment no. 122031400261-4.

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Authors and Affiliations

  1. Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 450054, Ufa, Russia

    N. K. Selezneva, A. M. Galeeva, Z. R. Valiullina & M. S. Miftakhov

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  1. N. K. Selezneva
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  2. A. M. Galeeva
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  3. Z. R. Valiullina
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  4. M. S. Miftakhov
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Correspondence to A. M. Galeeva.

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Selezneva, N.K., Galeeva, A.M., Valiullina, Z.R. et al. Synthesis of (3S,4S)-4-Acetyl-3-(1R)-1-hydroxyethyl-1-(4-methoxyphenyl)azetidin-2-one. Russ J Org Chem 58, 1676–1679 (2022). https://doi.org/10.1134/S1070428022110203

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  • DOI: https://doi.org/10.1134/S1070428022110203

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