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New Ozonolytic Synthesis of Keto Acids from 1-Alkylcycloalkenes

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Abstract

A new approach has been proposed for the synthesis of keto acids via ozonolytic cleavage of 1-alkylcycloalkenes in a mixture of methylene chloride and acetic acid, followed by oxidation of peroxide ozonolysis products with 30% H2O2–SeO2.

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Funding

This study was performed under financial support by the Russian Academy of Sciences, program “Fundamental Principles of Chemistry,” section no. 8: “Chemo-, Regio-, and Stereoselective Transformations of Terpenoids, Steroids, and Lipids in the Target-Oriented Synthesis of Low-Molec­ular-Weight Bioregulators” (state registry no. AAAA-A17117011910023-2, 2017) using the facilities of the Chemistry joint center (Ufa Institute of Chemistry, Russian Academy of Sciences) and Agidel joint center (Ufa Federal Research Center, Russian Academy of Sciences).

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Authors and Affiliations

  1. Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 450054, Ufa, Russia

    Yu. V. Myasoedova, K. S. Denisova, M. P. Yakovleva & G. Yu. Ishmuratov

Authors
  1. Yu. V. Myasoedova
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  2. K. S. Denisova
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  3. M. P. Yakovleva
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  4. G. Yu. Ishmuratov
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Corresponding author

Correspondence to M. P. Yakovleva.

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The authors declare the absence of conflict of interest.

Additional information

Translated from Zhurnal Organicheskoi Khimii, 2022, Vol. 58, No. 1, pp. 107–110 https://doi.org/10.31857/S0514749222010128.

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Myasoedova, Y.V., Denisova, K.S., Yakovleva, M.P. et al. New Ozonolytic Synthesis of Keto Acids from 1-Alkylcycloalkenes. Russ J Org Chem 58, 163–166 (2022). https://doi.org/10.1134/S1070428022010237

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  • DOI: https://doi.org/10.1134/S1070428022010237

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