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1,3-Dipolar Cycloaddition of Nitrones to Methyl {4-[(2E)-3-(4-Methoxyphenyl)prop-2-enoyl]phenyl}carbamate

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Abstract

1,3-Dipolar cycloaddition of nitrones to methyl {4-[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]­phenyl}carbamate regioselectively afforded the corresponding 2,3,4,5-tetrasubstituted isoxazolidines with high yields (85–90%).

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Funding

This study was performed under financial support by the Russian Foundation for Basic Research (project no. 19-03-00006A).

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Authors and Affiliations

  1. Astrakhan State University, 414000, Astrakhan, Russia

    A. V. Velikorodov & E. N. Kutlalieva

  2. Astrakhan State Medical University, Ministry of Health of the Russian Federation, 414000, Astrakhan, Russia

    A. V. Velikorodov, E. N. Kutlalieva & A. S. Zukhairaeva

  3. Southern Scientific Center, Russian Academy of Sciences, 344006, Rostov-on-Don, Russia

    V. P. Osipova & M. A. Polovinkina

Authors
  1. A. V. Velikorodov
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  2. E. N. Kutlalieva
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  3. V. P. Osipova
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  4. M. A. Polovinkina
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  5. A. S. Zukhairaeva
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Corresponding author

Correspondence to A. V. Velikorodov.

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The authors declare the absence of conflict of interest.

Additional information

Translated from Zhurnal Organicheskoi Khimii, 2022, Vol. 58, No. 1, pp. 76–81 https://doi.org/10.31857/S0514749222010074.

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Velikorodov, A.V., Kutlalieva, E.N., Osipova, V.P. et al. 1,3-Dipolar Cycloaddition of Nitrones to Methyl {4-[(2E)-3-(4-Methoxyphenyl)prop-2-enoyl]phenyl}carbamate. Russ J Org Chem 58, 60–64 (2022). https://doi.org/10.1134/S1070428022010079

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  • DOI: https://doi.org/10.1134/S1070428022010079

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