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Hindered Phenols in the Study of Structural Effectors of Antibacterial Activity

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Abstract

Derivatives of hindered phenols have antibacterial activity, the level of which can be associated with certain structural elements―structural effectors (SE). The SE criterion correlating structure with bioactivity was used in the analysis of the antibacterial activity of two groups of organic compounds: aliphatic alcohols and carboxylic acids. Evidence for a prognostic potential of the SE concept was obtained.

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REFERENCES

  1. Vol’eva, V.B., Komissarova, N.L., Ovsyannikova, M.N., Domnina, N.S., and Malkova, A.V., Structure Modification of Bioantioxidants Based on Hindered Phenols, Antioxidants in Systems of Varying. Complexity Chemical, Biochemical, and Biological Aspects. Shishkina, L.N., Goloshchapov, A.N., and Weisfeld, L.I., Eds., Toronto: Apple Academic Press, 2020, p. 3.

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Authors and Affiliations

  1. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 119334, Moscow, Russia

    V. B. Vol’eva, M. N. Ovsyannikova & A. V. Ryzhakova

Authors
  1. V. B. Vol’eva
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  2. M. N. Ovsyannikova
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  3. A. V. Ryzhakova
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Correspondence to A. V. Ryzhakova.

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The authors declare no conflict of interest.

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Translated from Zhurnal Organicheskoi Khimii, 2021, Vol. 57, No. 2, pp. 188–193 https://doi.org/10.31857/S051474922102004X.

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Vol’eva, V.B., Ovsyannikova, M.N. & Ryzhakova, A.V. Hindered Phenols in the Study of Structural Effectors of Antibacterial Activity. Russ J Org Chem 57, 160–164 (2021). https://doi.org/10.1134/S1070428021020044

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  • DOI: https://doi.org/10.1134/S1070428021020044

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