Skip to main content
Log in

Direct Etherification of a Single Primary Hydroxy Group of β-Cyclodextrin

  • Published:
Russian Journal of Organic Chemistry Aims and scope Submit manuscript

Abstract

The possibility of direct etherification of a single primary hydroxy group of β-cyclodextrin with a series of alcohols and diols has been demonstrated. In the reactions with diols, dimeric β-cyclodextrin could be obtained, which are interesting from the practical viewpoint. The structure of the isolated compounds has been confirmed by 1H and 13C NMR spectra.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Scheme
Scheme

REFERENCES

  1. Cyclodextrin Fundamentals, Reactivity and Analysis, Lichtfouse, E., Fourmentin, S., and Crini, G., Eds., Heidelberg: Springer, 2018. https://doi.org/10.1007/978-3-319-76159-6

  2. Shipilov, D.A., Kurochkina, G.I., Rasadkina, E.N., Vasyanina, L.K., Grachev, M.K., and Soboleva, N.O., Russ. J. Gen. Chem., 2015, vol. 85, p. 2605. https://doi.org/10.1134/S107036321511016X

    Article  CAS  Google Scholar 

  3. Shipilov, D.A., Kurochkina, G.I., Batalova, T.A., and Grachev, M.K., Russ. J. Org. Chem., 2015, vol. 51, p. 1395. https://doi.org/10.1134/S1070428015100061

    Article  CAS  Google Scholar 

  4. Grachev, M.K., Edunov, A.V., Kurochkina, G.I., Soboleva, N.O., Vasyanina, L.K., and Nifant’ev, E.E., Russ. Chem. Bull., Int. Ed., 2012, vol. 61, p. 181. https://doi.org/10.1007/S11172-012-0025-6

    Article  CAS  Google Scholar 

  5. Coates, J.H., Easton, C.J., Fryer, N.L., and Lincoln, S.F., Chem. Lett., 1994, vol. 23, p. 1153. https://doi.org/10.1246/cl.1994.1153

    Article  Google Scholar 

  6. Eftink, M.R., Andy, M.L., Bystrom, K., Permutter, H.D., and Kristol, D.S., J. Am. Chem. Soc., 1989, vol. 111, p. 6765. https://doi.org/10.1021/ja00199a041

    Article  CAS  Google Scholar 

  7. Liu, Y. and Chen, Y., Acc. Chem. Res., 2006, vol. 39, p. 681. https://doi.org/10.1021/ar0502275

    Article  CAS  PubMed  Google Scholar 

  8. Grachev, M.K., Terekhova, I.V., Shipilov, D.A., Kutyasheva, N.V., and Emelianova, E.Y., Russ. J. Bioorg. Chem., 2020, vol. 46, p. 14. https://doi.org/10.1134/S1068162020010021

    Article  CAS  Google Scholar 

  9. Khusnutdinov, R.I. and Bayguzina, A.R., Russ. J. Org. Chem., 2019, vol. 55, p. 903. https://doi.org/10.1134/S1070428019070017

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to N. V. Kutyasheva.

Ethics declarations

The authors declare the absence of conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kutyasheva, N.V., Kurochkina, G.I., Solomatin, E.A. et al. Direct Etherification of a Single Primary Hydroxy Group of β-Cyclodextrin. Russ J Org Chem 57, 121–125 (2021). https://doi.org/10.1134/S1070428021010188

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070428021010188

Keywords:

Navigation