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Potassium 1,1,3,3-Tetracyano-2-[2-(methoxycarbonyl)benzoyl]prop-2-enide in the Synthesis of Spiro-Fused Isobenzofuran Derivatives

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Abstract

Successive treatment of potassium 1,1,3,3-tetracyano-2-(2-(methoxycarbonyl)benzoyl)prop-2-enide with concentrated sulfuric acid and water gave 2-(5′-amino-4′-cyano-3-oxo-3H,3′H-spiro[[2]benzofuran-1,2′-furan]-3′-ylidene)propanedinitrile. The reaction of the title compound with sodium hydroxide, followed by neutralization with sulfuric acid afforded 4′-amino-3,3′,6′-trioxo-2′,3′,5′,6′-tetrahydro-3H-spiro[[2]benzofuran-1,1′-pyrrolo[3,4-c]pyridine]-7′-carbonitrile.

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Funding

This study was performed under financial support by the Russian Foundation for Basic Research (project no. 18-33-20120 mol_a_ved).

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Authors and Affiliations

  1. I.N. Ulʼyanov Chuvash State University, 428015, Cheboksary, Russia

    Ya. S. Kayukov, S. V. Karpov & A. A. Grigorʼev

  2. Chuvash State Agricultural Academy, 428003, Cheboksary, Russia

    O. V. Kayukova

Authors
  1. Ya. S. Kayukov
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  2. S. V. Karpov
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  3. A. A. Grigorʼev
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  4. O. V. Kayukova
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Correspondence to Ya. S. Kayukov or O. V. Kayukova.

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Kayukov, Y.S., Karpov, S.V., Grigorʼev, A.A. et al. Potassium 1,1,3,3-Tetracyano-2-[2-(methoxycarbonyl)benzoyl]prop-2-enide in the Synthesis of Spiro-Fused Isobenzofuran Derivatives. Russ J Org Chem 56, 1859–1861 (2020). https://doi.org/10.1134/S1070428020100322

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  • DOI: https://doi.org/10.1134/S1070428020100322

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