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Synthesis and Properties of 3-Substituted 2H-Chromen-2-ones

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Abstract

The condensation of salicylaldehyde with CH acids [p-methoxyacetoacetanilide, ethyl 3-amino-3-sulfanylidenepropanoate, 3-amino-N-aryl-3-sulfanylidenepropanamides, and ethyl 2-(1,3-thiazol-2- and -4-yl)acetates] afforded 3-substituted chromen-2-ones. Some properties of the products were studied. The structures of 3-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-2H-chromen-2-one, 2-oxo-2H-chromene-3-carboxamide, and 2-imino-N-(2-methoxyphenyl)-2H-chromene-3-carboxamide were determined by X-ray analysis.

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Funding

This study was financially supported by the “5–100” Program for increasing the rating of the People’s Friendship University of Russia. The X-ray diffraction studies were performed on the unique research setup “Kurchatov Synchrotron Radiation Source” supported by the Ministry of Science and Higher Education of the Russian Federation (project ID RFMEFI61917X0007).

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Correspondence to V. G. Nenaidenko.

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Dyachenko, I.V., Dyachenko, V.D., Dorovatovsky, P.V. et al. Synthesis and Properties of 3-Substituted 2H-Chromen-2-ones. Russ J Org Chem 56, 1123–1131 (2020). https://doi.org/10.1134/S1070428020070015

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