Skip to main content
SpringerLink
Log in

Reaction of 5-(Arylmethylidene)-2,4,6-pyrimidine2,4,6(1H,3H,5H)-triones with Morpholine N-Oxide

  • Published:
Russian Journal of Organic Chemistry Aims and scope Submit manuscript

Abstract

The reaction of 5-(arylmethylidene)-2,4,6-pyrimidine-2,4,6(1H,3H,5H)-triones with morpholine in the presence of hydrogen peroxide and catalytic amounts of sodium tungstate leads to the synthesis of 2-aryltetrahydro-1'H,2H-spiro(isoxazole[3,2-c][1,4]oxazine-3,5'-pyrimidine)-2',4',6'(3'H)-triones.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Scheme

Similar content being viewed by others

REFERENCES

  1. Tyrkov, A.G. and Yurtaeva, E.A., Russ. J. Org. Chem., 2019, vol. 52, p. 978. https://doi.org/10.1134/S1070428019070108

    Article  Google Scholar 

  2. Sivik, M.R. and Edmondson, S.D., Encyclopediaof Reagents for Organic Synthesis, Hoboken: Wiley, 2008, vol. 3. https://doi.org/10.1002/047084289x.rm216.pub2

  3. Yurtaeva, E.A. and Tyrkov, A.G., Russ. J. Org. Chem., 2016, vol. 52, p. 289. https://doi.org/10.1134/S1070428016020214

    Article  CAS  Google Scholar 

  4. Padwa, A., Koehler, K.F., and Rodriguez, A., J. Org.Chem., 1984, vol. 49, p. 282. https://doi.org/10.1021/jo00176a013

    Article  CAS  Google Scholar 

  5. Mashkovskii, M.D., Lekarstvennye sredstva (Drugs), Moscow: Novaya Volna, 2006.

  6. Luzhnova, S.A., Tyrkov, A.G., Gabitova, N.M., and Yurtaeva, E.A., Pharm. Chem. J., 2018, vol. 52, p. 506. https://doi.org/10.1007/s11094-018-1849-7

    Article  CAS  Google Scholar 

  7. Kirkhner, Yu., Tonkosloinaya khromatografiya (Thin Layer Chromatography), Moscow: Mir, 1981, vol. 1.

Download references

Author information

Authors and Affiliations

  1. Astrakhan State University, 414000, Astrakhan, Russia

    A. G. Tyrkov

Authors
  1. A. G. Tyrkov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. G. Tyrkov.

Ethics declarations

The author declares no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tyrkov, A.G. Reaction of 5-(Arylmethylidene)-2,4,6-pyrimidine2,4,6(1H,3H,5H)-triones with Morpholine N-Oxide. Russ J Org Chem 56, 939–941 (2020). https://doi.org/10.1134/S1070428020050309

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070428020050309

Keywords:

Search

Navigation