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Synthesis, Application, and Properties of Bis(1H-azol-1-yl)methanimines

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Abstract

The review considers methods of preparation and application of bis(1H-azol-1-yl)methanimines that are imino analogs of 1,1′-carbonylbisazoles widely used in the synthesis of various organic compounds, including natural ones. Methods of synthesis of a number of new symmetrical and unsymmetrical bisazolylmethanimines derived from imidazole, 2(4)-alkylimidazoles, and 1,2,4-triazole are described, and data on their hydrolytic stability in aqueous—organic medium (aqueous tetrahydrofuran) at 25°C and pH 7 and biological activity with respect to rat erythrocytes are given.

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Authors and Affiliations

  1. Samara National Research University, Samara, 443086, Russia

    P. P. Purygin & Yu. P. Zarubin

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  1. P. P. Purygin
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  2. Yu. P. Zarubin
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Correspondence to P. P. Purygin.

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Russian Text © The Author(s), 2020, published in Zhurnal Organicheskoi Khimii, 2020, Vol. 56, No. 1, pp. 129–139.

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Purygin, P.P., Zarubin, Y.P. Synthesis, Application, and Properties of Bis(1H-azol-1-yl)methanimines. Russ J Org Chem 56, 105–112 (2020). https://doi.org/10.1134/S1070428020010170

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