Abstract
New spiro heterocycles, spiro[benzo[h]chromene-4,3′-indoles] and spiro[benzo[f]chromene-1,3′-indoles], have been synthesized in 50–60% yield by three-component condensation of substituted isatins with malononitrile or ethyl cyanoacetate and naphthalen-1-ol or naphthalen-2-ol. The described reactions follow a cascade cyclization pathway and provide a regioselective method of synthesis of the title compounds.
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Russian Text © The Author(s), 2019, published in Zhurnal Organicheskoi Khimii, 2019, Vol. 55, No. 12, pp. 1822–1826.
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Poghosyan, S.H., Poghosyan, M.V. Synthesis of Spiro[benzo[h]chromene-4,3′-indoles] and Spiro[benzo[f]chromene-1,3′-indoles]. Russ J Org Chem 55, 1821–1825 (2019). https://doi.org/10.1134/S1070428019120029
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DOI: https://doi.org/10.1134/S1070428019120029