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Synthesis and Properties of Aminomethoxy Derivatives of 1-Phenoxy-3-(propylsulfanyl)propane

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Abstract

The condensation of 1-phenoxy-3-(propylsulfanyl)propan-2-ol with formaldehyde and secondary aliphatic and heterocyclic amines afforded new aminomethoxy derivatives of 1-phenoxy-3-(propylsulfanyl)- propane in 69–77% yields. The product structure was confirmed by elemental analyses and IR and 1H and 13C NMR spectra. The synthesized compounds were assayed as antiseptics against bacteria and fungi and were shown to be more efficient antimicrobial agents than those currently used in medicine.

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Funding

This study was performed in the framework of contract no. 1/18 (April 12, 2018) on scientific and technological collaboration between the Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, and Mamedaliev Institute of Petrochemical Processes, National Academy of Sciences of Azerbaijan.

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Authors and Affiliations

  1. Azerbaijan State Pedagogical University, Baku, Azerbaijan

    I. A. Jafarov & A. D. Astanova

  2. Institute of Petrochemical Processes, National Academy of Sciences of Azerbaijan, Baku, Azerbaijan

    E. H. Mammadbayli

  3. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow, Russia

    K. A. Kochetkov

  4. Azerbaijan State University of Oil and Industry, Baku, Azerbaijan

    L. M. Maharramova

Authors
  1. I. A. Jafarov
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  2. E. H. Mammadbayli
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  3. K. A. Kochetkov
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  4. A. D. Astanova
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  5. L. M. Maharramova
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Corresponding author

Correspondence to E. H. Mammadbayli.

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No conflict of interests is declared by the authors.

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Russian Text © The Author(s), 2019, published in Zhurnal Organicheskoi Khimii, 2019, Vol. 55, No. 9, pp. 1352–1358.

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Jafarov, I.A., Mammadbayli, E.H., Kochetkov, K.A. et al. Synthesis and Properties of Aminomethoxy Derivatives of 1-Phenoxy-3-(propylsulfanyl)propane. Russ J Org Chem 55, 1275–1279 (2019). https://doi.org/10.1134/S1070428019090021

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  • DOI: https://doi.org/10.1134/S1070428019090021

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