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Synthesis of New Sulfur-Substituted Pentacyclic 1,2,4-Triazolopyrimidine Derivatives

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Abstract

Pentacyclic heterocyclic compounds containing a 1,2,4-triazole ring have been synthesized from [5-(2-methylpropyl)-1,2,3,4-tetrahydropyrimido[4′,5′: 4,5]thieno[2,3-c]isoquinolin-8-yl]hydrazine. The synthesized [1,2,4]triazolo[4,3-c]pyrimidine derivatives have been found to undergo Dimroth rearrangement in both acidic and basic media.

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Authors and Affiliations

  1. Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, Yerevan, 0014, Armenia

    S. N. Sirakanyan, E. K. Hakobyan & A. A. Hovakimyan

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  1. S. N. Sirakanyan
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  2. E. K. Hakobyan
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  3. A. A. Hovakimyan
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Correspondence to S. N. Sirakanyan.

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Russian Text © The Author(s), 2019, published in Zhurnal Organicheskoi Khimii, 2019, Vol. 55, No. 3, pp. 360–366.

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Sirakanyan, S.N., Hakobyan, E.K. & Hovakimyan, A.A. Synthesis of New Sulfur-Substituted Pentacyclic 1,2,4-Triazolopyrimidine Derivatives. Russ J Org Chem 55, 308–313 (2019). https://doi.org/10.1134/S1070428019030059

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  • DOI: https://doi.org/10.1134/S1070428019030059

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