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Synthesis of a Precursor of the Antiviral Agent A-315675

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Abstract

Ethyl 2-(acetylamino)-3-methoxy-3-methylhexanoate, a key precursor of the known pyrrolidine antiviral agent A-315675, was synthesized starting with the readily available acetoacetic ester.

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Authors and Affiliations

  1. Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054, Russia

    V. A. Egorov & F. A. Gimalova

Authors
  1. V. A. Egorov
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  2. F. A. Gimalova
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Correspondence to F. A. Gimalova.

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Russian Text © V.A. Egorov, F.A. Gimalova, 2019, published in Zhurnal Organicheskoi Khimii, 2019, Vol. 55, No. 2, pp. 294–298.

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Egorov, V.A., Gimalova, F.A. Synthesis of a Precursor of the Antiviral Agent A-315675. Russ J Org Chem 55, 241–244 (2019). https://doi.org/10.1134/S1070428019020167

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  • DOI: https://doi.org/10.1134/S1070428019020167

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