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Synthesis and Biological Activity of Substituted Spiro[chromene-4,3′-indoles] and Spiro[indole-3,4′-quinolines]

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Abstract

New substituted spiro[chromene-4,3′-indoles] and spiro[indole-3,4′-quinolines] have been synthesized in 35–65% yields by one-pot regioselective three-component condensation of N-substituted isatins with two active methylene compounds.

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Authors and Affiliations

  1. Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, Yerevan, 0014, Armenia

    S. A. Pogosyan, M. V. Pogosyan, L. R. Aleksanyan, A. S. Safaryan & A. G. Arakelyan

Authors
  1. S. A. Pogosyan
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  2. M. V. Pogosyan
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  3. L. R. Aleksanyan
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  4. A. S. Safaryan
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  5. A. G. Arakelyan
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Corresponding author

Correspondence to S. A. Pogosyan.

Additional information

Original Russian Text © S.A. Pogosyan, M.V. Pogosyan, L.R. Aleksanyan, A.S. Safaryan, A.G. Arakelyan, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 12, pp. 1845–1848.

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Pogosyan, S.A., Pogosyan, M.V., Aleksanyan, L.R. et al. Synthesis and Biological Activity of Substituted Spiro[chromene-4,3′-indoles] and Spiro[indole-3,4′-quinolines]. Russ J Org Chem 54, 1860–1863 (2018). https://doi.org/10.1134/S1070428018120254

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  • DOI: https://doi.org/10.1134/S1070428018120254

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