Abstract
A one-pot preparative synthesis of 9-substituted 2-alkyl(aryl)imidazo[1,2-a]benzimidazole-3-carbonitriles from the corresponding 3-carbaldehydes and hydroxylamine O-sulfonic acid has been developed.
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Mashkovskii, M.D., Lekarstvennye sredstva (Medicines), Moscow: Novaya Volna, 1996, 12th ed.
Fleming, F.F., Yao, L., Ravikumar, P.C., Funk, L., and Shook, B.C., J. Med. Chem., 2010, vol. 53, p. 7902.
Spasov, A.A., Chernikov, A.A., Anisimova, V.A., Kuz’-menko, T.A., and Osipova, M.M., Pharm. Chem. J., 2000, vol. 34, no. 2, p.48.
Anisimova, V.A., Spasov, A.A., Kosolapov, V.A., Kucheryavenko, A.F., Ostrovskii, O.V., Larionov, N.P., and Libinzon, R.E., Pharm. Chem. J., 2005, vol. 39, no. 9, p.476.
Han, X., Pin, S.S., Burris, K., Fung, L.K., Huang, S., Taber, M.T., Zhang, J., and Dubowchik, G.M., Bioorg. Med. Chem. Lett., 2005, vol. 15, p. 4029.
Anisimova, V.A., Spasov, A.A., Tolpygin, I.E., Minkin, V.I., Chernikov, M.V., Yakovlev, D.S., Stukovina, A.Yu., Goryagin, I.I., Grechko, O.Yu., Kirillova, N.V., Kosolapov, V.A., Tibir’kova, E.V., Salaznikova, O.A., Naumenko, L.V., and Gurova, N.A., Pharm. Chem. J., 2010, vol. 44, no. 7, p.345.
Anisimova, V.A., Spasov, A.A., Grechko, O.Yu., Eliseeva, N.V., Tolpygin, I.E., and Minkin, V.I., RU Patent no. 2 412 187, 2011; Byull. Izobret., 2011, no.5.
Kalitin, K.Yu., Spasov, A.A., Grechko, O.Yu., Sukhov, A.G., Vislobokov, A.I., Anisimova, V.A., and Matukhno, A.E., Eksp. Klin. Farmakol., 2017, vol. 80, no. 9, p.28.
Kuz’menko, T.A., Kuz’menko, V.V., and Anisimova, V.A., Russ. J. Org. Chem., 1995, vol. 31, p.96.
Streithm J., Fizet, Ch., and Fritz, H., Helv. Chim. Acta, 1976, vol. 59, p. 2786.
Kuzmenko, V.V. and Pozharskii, A.F., Advances in Heterocyclic Chemistry, Katritzky, A.R., Ed., Amsterdam: Elsevier, 1992, vol. 53, p.85.
Simonov, A.M., Anisimova, V.A., and Grushina, L.E., Chem. Heterocycl. Compd., 1970, vol. 6, no. 6, p.778.
Anisimova, V.A., Avdyunina, N.I., Pozharskii, A.F., Simonov, A.M., and Talanova, L.R., Chem. Heterocycl. Compd., 1980, vol. 16, p.409.
Gel’man, N.E., Terent’eva, E.A., Shanina, T.M., and Kiparenko, L.M., Metody kolichestvennogo organicheskogo elementnogo analiza (Methods of Quantitative Organic Elemental Analysis), Moscow: Khimiya, 1987.
Anisimova, V.A., Simonov, A.M., and Borisova, T.A., Chem. Heterocycl. Compd., 1973, vol. 9, no. 6, p. 726.
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Original Russian Text © T.A. Kuz’menko, L.N. Divaeva, V.A. Anisimova, A.S. Morkovnik, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 9, pp. 1364–1368.
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Kuz’menko, T.A., Divaeva, L.N., Anisimova, V.A. et al. Synthesis of 9-Substituted 2-Alkyl(aryl)imidazo-[1,2-a]benzimidazole-3-carbonitriles. Russ J Org Chem 54, 1378–1382 (2018). https://doi.org/10.1134/S107042801809018X
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DOI: https://doi.org/10.1134/S107042801809018X