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New Strategy of the Synthesis of 3,4-Dihydropyrimido[1,2-a]benzimidazol-2(1H)-ones

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Abstract

A new procedure has been developed for preparative synthesis of 3,4-dihydropyrimido[1,2-a]-benzimidazol-2(1H)-ones by thermal intramolecular heterocyclization of 3-[2-(propylsulfanyl)- and 2-(benzylsulfanyl)-1H-benzimidazol-1-yl]propanehydrazides and 3-[2-(benzylsulfanyl)-1H-benzimidazol-1-yl]-propanamide.

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Authors and Affiliations

  1. Litvinenko Institute of Physical Organic and Coal Chemistry, ul. R. Lyuksemburg 70, Donetsk, 83114, Ukraine

    A. O. Kharaneko

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  1. A. O. Kharaneko
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Correspondence to A. O. Kharaneko.

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Original Russian Text © A.O. Kharaneko, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 9, pp. 1350–1354.

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Kharaneko, A.O. New Strategy of the Synthesis of 3,4-Dihydropyrimido[1,2-a]benzimidazol-2(1H)-ones. Russ J Org Chem 54, 1363–1368 (2018). https://doi.org/10.1134/S1070428018090166

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  • DOI: https://doi.org/10.1134/S1070428018090166

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