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Reactions of Secondary Amines with Dichlorocarbene Generated in Aqueous–Alkaline Medium in the Presence of N-Methylmorpholine N-Oxide

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Abstract

Dichlorocarbene generated from chloroform in aqueous–alkaline medium in the presence of N-methylmorpholine N-oxide is converted to phosgene which reacts in situ with secondary amines to afford tetrasubstituted ureas.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, Yerevan, 0014, Armenia

    A. G. Hasratyan, G. A. Bagdasaryan, S. S. Hayotsyan & H. S. Attaryan

Authors
  1. A. G. Hasratyan
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  2. G. A. Bagdasaryan
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  3. S. S. Hayotsyan
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  4. H. S. Attaryan
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Corresponding author

Correspondence to H. S. Attaryan.

Additional information

Original Russian Text © A.G. Hasratyan, G.A. Bagdasaryan, S.S. Hayotsyan, H.S. Attaryan, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 6, pp. 951–952.

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Hasratyan, A.G., Bagdasaryan, G.A., Hayotsyan, S.S. et al. Reactions of Secondary Amines with Dichlorocarbene Generated in Aqueous–Alkaline Medium in the Presence of N-Methylmorpholine N-Oxide. Russ J Org Chem 54, 959–960 (2018). https://doi.org/10.1134/S1070428018060258

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  • DOI: https://doi.org/10.1134/S1070428018060258

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