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Synthesis of 1,2-Diazepines by the Bischler–Napieralski Reaction

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Abstract

A new strategy has been proposed for the synthesis of 5H-[1]benzofuro[2,3-d][1,2]diazepines containing two aryl substituents in the diazepine fragment. The key stage of the synthesis is intramolecular cyclization of the corresponding hydrazides under the Bischler–Napieralski reaction conditions.

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Correspondence to A. B. Eresko.

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Original Russian Text © A.V. Muratov, S.A. Grebenyuk, A.B. Eresko, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 6, pp. 860–864.

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Muratov, A.V., Grebenyuk, S.A. & Eresko, A.B. Synthesis of 1,2-Diazepines by the Bischler–Napieralski Reaction. Russ J Org Chem 54, 861–866 (2018). https://doi.org/10.1134/S1070428018060064

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  • DOI: https://doi.org/10.1134/S1070428018060064

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