Russian Journal of Organic Chemistry

, Volume 53, Issue 10, pp 1564–1572 | Cite as

Nitro derivatives of pyrrolo[3,2-d]pyrimidine-2,4-diones: Synthesis of amines and new polynuclear heterocycles based thereon

  • Yu. N. Tkachenko
  • L. D. Popov
  • A. F. Pozharskii
  • S. A. Borodkin
  • S. I. Levchenkov


The nitration of 1,3-dimethylpyrrolo[3,2-d]pyrimidine-2,4-diones under different conditions led to the formation of their 6(7)-mono- and 6,7-dinitro derivatives which were reduced to the corresponding amines. The latter reacted with α- and β-dicarbonyl compounds, as well as with ortho-quinones to give a number of new polycyclic heteroaromatic systems.


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Copyright information

© Pleiades Publishing, Ltd. 2017

Authors and Affiliations

  • Yu. N. Tkachenko
    • 1
  • L. D. Popov
    • 1
  • A. F. Pozharskii
    • 1
  • S. A. Borodkin
    • 1
  • S. I. Levchenkov
    • 1
    • 2
  1. 1.Southern Federal UniversityRostov-on-DonRussia
  2. 2.Southern Scientific CenterRussian Academy of SciencesRostov-on-DonRussia

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