Skip to main content
Log in

Condensation of chloromethyl propargyl ether with nitriles

  • Short Communications
  • Published:
Russian Journal of Organic Chemistry Aims and scope Submit manuscript

Abstract

Reactions of aromatic and aliphatic nitriles with chloromethyl propargyl ether in the presence of activated zinc followed by treatment with water in the presence of H3PMo12O40 afforded β-oxoethers.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Blaise, E.E., C. R. Hebd. Seances Acad. Sci., 1901, vol. 132, p. 478.

    CAS  Google Scholar 

  2. Lee, J.H., Choi, B.S., Chang, J.H., Lee, H.B., Yoon, J.-Y., Lee, J., and Shin, H., J. Org. Chem., 2007, vol. 72, p. 10261. doi 10.1021/jo701743m

    Article  CAS  Google Scholar 

  3. Rao, H.S.P., Rafi, S., and Padmavathy, K., Tetrahedron, 2008, vol. 64, p. 8037. doi 10.1016/j.tet.2008.05.109

    Article  Google Scholar 

  4. Chun, Y.S., Ryu, K.Y., Ko, Y.O., Hong, J.Y., Hong, J., Shin, H., and Lee, S.-g., J. Org. Chem., 2009, vol. 74, p. 7556. doi 10.1021/jo901642t

    Article  CAS  Google Scholar 

  5. Hoang, C.T., Bouillère, F., Johannesen, S., Zulauf, A., Panel, C., Pouilhès, A., Gori, D., Alezra, V., and Kouklovsky, C., J. Org. Chem., 2009, vol. 74, p. 4177. doi 10.1021/jo900324d

    Article  CAS  Google Scholar 

  6. Kim, J.H., Shin, H., and Lee, S.-g., J. Org. Chem., 2012, vol. 77, p. 1560. doi 10.1021/jo201964a

    Article  CAS  Google Scholar 

  7. Kim, J.H., Chun, Y.S., and Lee, S.-g., J. Org. Chem., 2013, vol. 78, p. 11483. doi 10.1021/jo402015n

    Article  CAS  Google Scholar 

  8. Sakthivel, K. and Srinivasan, K., J. Org. Chem., 2014, vol. 79, p. 3244. doi 10.1021/jo500137m

    Article  CAS  Google Scholar 

  9. Kim, J.H., Choi, S.Y., Bouffard, J., and Lee, S.-g., J. Org. Chem., 2014, vol. 79, p. 9253. doi 10.1021/jo501672c

    Article  CAS  Google Scholar 

  10. Zil’berman, E.N., Reaktsii nitrilov (Reactions of Nitriles), Moscow Khimiya, 1972.

    Google Scholar 

  11. Metody elementoorganicheskoi khimii (Methods of Organoelemental Chemistry), Nesmeyanov, A.N. and Kocheshkov, K.A., Eds., Moscow Nauka, 1964.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to G. M. Talybov.

Additional information

Original Russian Text © G.M. Talybov, 2017, published in Zhurnal Organicheskoi Khimii, 2017, Vol. 53, No. 2, pp. 295–296.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Talybov, G.M. Condensation of chloromethyl propargyl ether with nitriles. Russ J Org Chem 53, 296–298 (2017). https://doi.org/10.1134/S1070428017020269

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070428017020269

Navigation