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Regio- and stereoselective (3 + 2)-cycloaddition of nitrile oxides and nitrones to N-vinylindole

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Abstract

1,3-Dipolar cycloaddition of nitrile oxides and nitrones to N-vinylindole proceeds regioselectively at the exocyclic multiple bond to form 5-indolyl-substituted isoxazolines and isoxazolidines in good yields.

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Authors and Affiliations

  1. St. Petersburg State University, Universitetskaya nab. 7/9, St. Petersburg, 199034, Russia

    M. M. Efremova, R. R. Kostikov, A. G. Larina & A. P. Molchanov

Authors
  1. M. M. Efremova
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  2. R. R. Kostikov
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  3. A. G. Larina
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  4. A. P. Molchanov
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Corresponding author

Correspondence to M. M. Efremova.

Additional information

Original Russian Text © M.M. Efremova, R.R. Kostikov, A.G. Larina, A.P. Molchanov, 2017, published in Zhurnal Organicheskoi Khimii, 2017, Vol. 53, No. 2, pp. 251–254.

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Efremova, M.M., Kostikov, R.R., Larina, A.G. et al. Regio- and stereoselective (3 + 2)-cycloaddition of nitrile oxides and nitrones to N-vinylindole. Russ J Org Chem 53, 246–250 (2017). https://doi.org/10.1134/S107042801702018X

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  • DOI: https://doi.org/10.1134/S107042801702018X

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