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Synthesis of 1-(arylsulfonyl)pyrrolidines from phenols and 1-[(4-chlorophenyl)sulfonyl]-2-ethoxypyrrolidine

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Abstract

Acid-catalyzed reaction of 1-[(4-chlorophenyl)sulfonyl]-2-ethoxypyrrolidine with phenols leads to the formation of new 1-(arylsulfonyl)pyrrolidines. The reaction proceeds under mild conditions and may be used as a convenient method for the synthesis of pyrrolidine-1-sulfonylarene derivatives containing a phenol fragment in the position 2.

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Authors and Affiliations

  1. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Academika Arbuzova 8, Kazan, 420088, Russia

    A. V. Smolobochkin, A. S. Gazizov, A. R. Burilov & M. A. Pudovik

  2. Kazan National Research Technological University, Kazan, Russia

    E. A. Anikina

Authors
  1. A. V. Smolobochkin
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  2. E. A. Anikina
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  3. A. S. Gazizov
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  4. A. R. Burilov
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  5. M. A. Pudovik
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Corresponding author

Correspondence to A. S. Gazizov.

Additional information

Original Russian Text © A.V. Smolobochkin, E.A. Anikina, A.S. Gazizov, A.R. Burilov, M.A. Pudovik, 2017, published in Zhurnal Organicheskoi Khimii, 2017, Vol. 53, No. 2, pp. 209–212.

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Smolobochkin, A.V., Anikina, E.A., Gazizov, A.S. et al. Synthesis of 1-(arylsulfonyl)pyrrolidines from phenols and 1-[(4-chlorophenyl)sulfonyl]-2-ethoxypyrrolidine. Russ J Org Chem 53, 199–202 (2017). https://doi.org/10.1134/S1070428017020099

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  • DOI: https://doi.org/10.1134/S1070428017020099

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